Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 7/20 | 0.54 |
| ▸ | CES1 | P23141 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13718665 | 0.80 | AKR1C1 (0.57) | AKR1C1CES2CES1LMNAMAPT | |
| SCHEMBL11886125 | 0.80 | AKR1C1 (0.57) | AKR1C1CES2CES1LMNAMAPT | |
| SCHEMBL10664130 | 0.80 | KMT2A (0.57) | AKR1C1CES2CES1LMNAMAPT | |
| SCHEMBL626786 | 0.80 | AKR1C1 (0.57) | AKR1C1CES2CES1LMNAMAPT | |
| SCHEMBL11219395 | 0.78 | AKR1C1 (0.73) | AKR1C1CES2CES1LMNAMAPT | |
| SCHEMBL11219398 | 0.78 | AKR1C1 (0.73) | AKR1C1CES2CES1LMNAMAPT | |
| Bicarbonate SCHEMBL28922000 | 0.77 | ESR1 (0.65) | AKR1C1LMNAMAPTALDH1A1KMT2A | |
| SCHEMBL4730607 | 0.77 | AKR1C1 (0.59) | AKR1C1CES2CES1LMNAMAPT | |
| SCHEMBL112002 | 0.77 | AKR1C1 (0.59) | AKR1C1CES2CES1LMNAMAPT | |
| SCHEMBL7101077 | 0.77 | AKR1C1 (0.53) | AKR1C1CES2CES1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2009073761-A | LEPTIN PRODUCTION PROMOTER | NIPPON SEIBUTSU KAGAKU KENKYUSHO:KK | 2009-04-09 | — | — | JP | disclosed |