SCHEMBL7101077

SCHEMBL7101077

NC(=Cc1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 1/20 0.53
CES2 O00748 5/20 0.52
CES1 P23141 4/20 0.52
MAPT P10636 4/20 0.48
POLB P06746 2/20 0.48
RECQL P46063 2/20 0.48
CYP3A4 P08684 1/20 0.48
PARP1 P09874 1/20 0.48
TSHR P16473 1/20 0.48
CYP2C19 P33261 1/20 0.48
BLM P54132 1/20 0.48
PMP22 Q01453 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
MCL1 Q07820 1/20 0.47
LMNA P02545 3/20 0.46
ALDH1A1 P00352 3/20 0.46
KMT2A Q03164 3/20 0.46
KDM4E B2RXH2 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29536184 1.00 AKR1C1 (0.53) AKR1C1CES2CES1MAPTPOLB
SCHEMBL10487066 0.83 CES2 (0.52) AKR1C1CES2CES1MAPTPOLB
SCHEMBL792779 0.80 AKR1C3 (0.56) AKR1C1MAPTPOLBRECQLCYP3A4
SCHEMBL1081471 0.80 AKR1C3 (0.56) AKR1C1MAPTPOLBRECQLCYP3A4
SCHEMBL20049735 0.80 MCL1 (0.57) AKR1C1MAPTPOLBRECQLCYP3A4
SCHEMBL181651 0.80 MCL1 (0.52) AKR1C1MAPTPOLBRECQLCYP3A4
SCHEMBL5982913 0.80 AKR1C3 (0.56) AKR1C1MAPTPOLBRECQLCYP3A4
SCHEMBL17397066 0.80 MCL1 (0.57) AKR1C1MAPTPOLBRECQLCYP3A4
SCHEMBL11594648 0.80 MCL1 (0.57) AKR1C1MAPTPOLBRECQLCYP3A4
SCHEMBL7044923 0.79 MCL1 (0.48) AKR1C1TSHRMCL1ALDH1A1AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 399 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119823729-A Composition for preparing cooling liquid, preparation method and application thereof 张家港迪克汽车化学品有限公司 2025-04-15 CN claimed
CN-106749235-B The preparation method of poly-substituted quinoline and azole derivatives 西南大学 2019-02-19 CN claimed
CN-105017056-B Phenylpropen ketone derivatives and its preparation method and pharmaceutical composition and purposes 中国医学科学院药物研究所 2019-02-01 CN claimed
CN-108863930-A A kind of synthetic method of thio -2,3- dihydroquinoline -4 (1H) the -one class compound of 3- 太原理工大学 2018-11-23 CN claimed
CN-106243089-B 6- substitutions -2- (benzimidazolyl-2 radicals-methylene sulfenyl) pyrimidines of 4 construction units containing chalcone and its preparation method and application 郑州大学 2018-05-15 CN claimed
CN-106749235-A The preparation method of poly-substituted quinoline and azole derivatives 西南大学 2017-05-31 CN claimed
CN-106243089-A 46 replacement 2 (benzimidazole 2 methylene sulfenyl) pyrimidines containing chalcone construction unit and its production and use 郑州大学 2016-12-21 CN claimed
CN-105017056-A Phenyl acrylketone derivative and preparation method, drug composition and application thereof INST MATERIA MEDICA CAMS 2015-11-04 CN claimed
CN-104769070-A Uv-curable silicone adhesive compositions 3M INNOVATIVE PROPERTIES CO 2015-07-08 CN claimed
CN-104769059-A UV-curable silicone release compositions 3M INNOVATIVE PROPERTIES CO 2015-07-08 CN claimed
CN-103360338-B Preparation method of chalconebenzothiazoleamide derivatives, and use of derivatives XINJIANG TECH INST PHYSICS CAS 2015-04-01 CN claimed
CN-102146216-B Monoazo and polyazo dyes favorable for health and synthesis method thereof UNIV ZHENGZHOU 2013-11-13 CN claimed
CN-103360338-A Preparation method of chalconebenzothiazoleamide derivatives, and use of derivatives XINJIANG TECH INST PHYSICS CAS 2013-10-23 CN claimed
CN-103342653-A Preparation method and application of chalcone amide derivatives XINJIANG TECH INST PHYSICS CAS 2013-10-09 CN claimed
CN-101357902-B Method for preparing N- formyl-2H-4chloroquinoline derivate UNIV ZHEJIANG TECHNOLOGY 2011-06-29 CN claimed
CN-101357902-A Method for preparing N- formyl-2H-4chloroquinoline derivate UNIV ZHEJIANG TECHNOLOGY (CN) 2009-02-04 CN claimed
US-20260042729-A1 FUNCTIONALIZED DIACETYLENE MONOMERS, THEIR POLYMERIZATION AND USES THEREOF B G NEGEV TECHNOLOGIES AND APPLICATIONS LTD AT BEN GURION UNIV (IL) 2026-02-12 US disclosed
CN-119823729-A Composition for preparing cooling liquid, preparation method and application thereof 张家港迪克汽车化学品有限公司 2025-04-15 CN disclosed
CN-1216209-A ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE IDEMITSU KOSAN CO (JP) 1999-05-05 CN disclosed
CN-1168132-A organic electroluminescent device, organic thin film and triamine compound IDEMITSU KOSAN CO (JP) 1997-12-17 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042729-A1 FUNCTIONALIZED DIACETYLENE MONOMERS, THEIR POLYMERIZATION AND USES THEREOF ASIC1, ASIC3, CDY1; CDY1B AKR1C1 1048/4885CES2 4035/4885CES1 4366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.