Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET3 | O43151 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | FBXL19 | Q6PCT2 | 2/20 | 0.53 |
| ▸ | CXXC5 | Q7LFL8 | 2/20 | 0.53 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.53 |
| ▸ | CXXC4 | Q9H2H0 | 2/20 | 0.53 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 11/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.47 |
| ▸ | DPP4 | P27487 | 8/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3945170 | 0.91 | TET3 (0.51) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL3944992 | 0.80 | CCR1 (0.66) | CCR1 | |
| SCHEMBL10291591 | 0.79 | CCR1 (0.64) | CCR1 | |
| SCHEMBL3945164 | 0.77 | OPRM1 (0.64) | OPRM1CCR1 | |
| Trifluoroacetic Acid SCHEMBL2159087 | 0.75 | CCR1 (0.57) | CCR1 | |
| SCHEMBL2159166 | 0.75 | OPRM1 (0.46) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL2159164 | 0.75 | OPRM1 (0.46) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL3931269 | 0.75 | KMT2A (0.71) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL10292085 | 0.75 | CCR1 (0.64) | DPP7DPP8DPP9DPP4CCR1 | |
| SCHEMBL10291726 | 0.75 | CCR1 (0.64) | DPP7DPP8DPP9DPP4CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049486-A2 | PIPERIDINYL DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Bristol-Myers Squibb Company (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2007092681-A2 | PIPERIDINYL DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-16 | — | — | WO | disclosed |