Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4030823 | 0.85 | ALDH1A1 (0.53) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL3950920 | 0.84 | ALDH1A1 (0.62) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL3950434 | 0.84 | ALDH1A1 (0.64) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL3944219 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MAPTL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL4158477 | 0.83 | MAPT (0.60) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL3950431 | 0.83 | MAPT (0.60) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL4211551 | 0.82 | MAPT (0.59) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL3941329 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL3942658 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL4038215 | 0.80 | ALDH1A1 (0.57) | ALDH1A1MAPTL3MBTL1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | claimed |