Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28222420 | 0.89 | — | — | |
| SCHEMBL8467008 | 0.84 | SRD5A1 (0.30) | SRD5A1 | |
| SCHEMBL8459694 | 0.84 | SRD5A1 (0.30) | SRD5A1 | |
| SCHEMBL26673240 | 0.80 | SRD5A1 (0.38) | SRD5A1 | |
| SCHEMBL8469381 | 0.80 | SRD5A1 (0.30) | SRD5A1 | |
| SCHEMBL3944336 | 0.79 | SRD5A1 (0.35) | SRD5A1 | |
| SCHEMBL18019798 | 0.79 | SRD5A1 (0.38) | SRD5A1 | |
| SCHEMBL18150856 | 0.78 | SRD5A1 (0.37) | SRD5A1 | |
| SCHEMBL9998683 | 0.78 | SRD5A1 (0.37) | SRD5A1 | |
| SCHEMBL18289470 | 0.77 | SRD5A1 (0.43) | SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049475-A1 | CYCLOHEXYL SUBSTITUTED PYRROLIDINONES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 | Eli Lilly & Company (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2007127704-A1 | CYCLOHEXYL SUBSTITUTED PYRROLIDINONES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 | ELI LILLY AND COMPANY (US) | 2007-11-08 | — | — | WO | disclosed |