Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8467008 | 0.85 | SRD5A1 (0.30) | SRD5A1 | |
| SCHEMBL8459694 | 0.85 | SRD5A1 (0.30) | SRD5A1 | |
| SCHEMBL3944528 | 0.80 | SRD5A1 (0.35) | SRD5A1 | |
| SCHEMBL9055278 | 0.78 | — | — | |
| SCHEMBL9055276 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL9056700 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL9056699 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL8325712 | 0.77 | — | — | |
| SCHEMBL12534015 | 0.73 | SRD5A1 (0.38) | SRD5A1 | |
| SCHEMBL28222420 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789571-A4 | CYCLIC AMIDINE ANALOGS AS INHIBITORS OF NITRIC OXIDE SYNTHASE | MERCK & CO INC (US) | 1999-04-14 | — | — | EP | disclosed |
| EP-0789571-A1 | CYCLIC AMIDINE ANALOGS AS INHIBITORS OF NITRIC OXIDE SYNTHASE | Merck & Co., Inc. (US) | 1997-08-20 | — | — | EP | disclosed |
| WO-1996014844-A1 | CYCLIC AMIDINE ANALOGS AS INHIBITORS OF NITRIC OXIDE SYNTHASE | MERCK & CO., INC. (US) | 1996-05-23 | — | — | WO | disclosed |