Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952986 | 0.89 | ADORA2B (0.39) | — | |
| SCHEMBL1874349 | 0.87 | TLR7 (0.54) | TLR7 | |
| SCHEMBL3953928 | 0.86 | — | — | |
| SCHEMBL3951639 | 0.86 | TLR7 (0.53) | TLR7 | |
| SCHEMBL3945305 | 0.85 | TLR7 (0.51) | TLR7 | |
| SCHEMBL3946649 | 0.84 | TLR7 (0.54) | TLR7 | |
| SCHEMBL3947466 | 0.83 | TLR7 (0.49) | TLR7 | |
| SCHEMBL3946758 | 0.82 | JAK2 (0.38) | — | |
| SCHEMBL3954816 | 0.81 | — | — | |
| SCHEMBL3945741 | 0.81 | TLR9 (0.42) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009022185-A2 | 6, 6-FUSED HETEROCYCLES, THEIR PHARMACEUTICAL COMPOSITIONS AND METHOS OF USE | ASTRAZENECA AB (SE) | 2009-02-19 | — | — | WO | disclosed |