Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 17/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4892097 | 1.00 | ALDH1A1 (0.51) | ALDH1A1KDM1AHRH3HTR2AHTR2C | |
| SCHEMBL3944651 | 1.00 | ALDH1A1 (0.51) | ALDH1A1KDM1AHRH3HTR2AHTR2C | |
| SCHEMBL4890920 | 1.00 | ALDH1A1 (0.51) | ALDH1A1KDM1AHRH3HTR2AHTR2C | |
| SCHEMBL4889853 | 0.86 | HTR2C (0.47) | KDM1AHRH3HTR2CHTR2B | |
| SCHEMBL776338 | 0.86 | HTR2C (0.47) | KDM1AHRH3HTR2CHTR2B | |
| SCHEMBL4889856 | 0.86 | HTR2C (0.47) | KDM1AHRH3HTR2CHTR2B | |
| SCHEMBL4886693 | 0.86 | HTR2C (0.47) | KDM1AHRH3HTR2CHTR2B | |
| SCHEMBL776339 | 0.86 | HTR2C (0.47) | KDM1AHRH3HTR2CHTR2B | |
| SCHEMBL4886650 | 0.86 | HTR2C (0.47) | KDM1AHRH3HTR2CHTR2B | |
| SCHEMBL4896173 | 0.86 | HTR2C (0.47) | KDM1AHRH3HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049472-A2 | CYCLOPROPYL AMINE DERIVATIVES AS HISTAMIN H3 RECEPTOR MODULATORS | Abbott Laboratories (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2007150010-A2 | CYCLOPROPYL AMINE DERIVATIVES AS HISTAMIN H3 RECEPTOR MODULATORS | ABBOTT LABORATORIES (US) | 2007-12-27 | — | — | WO | disclosed |