SCHEMBL39447

SCHEMBL39447

CC(C)CC(C)Nc1ccc(Nc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 1.00
HSD17B10 Q99714 5/20 1.00
ALOX15 P16050 4/20 1.00
TSHR P16473 4/20 1.00
ALOX12 P18054 4/20 1.00
CYP3A4 P08684 4/20 1.00
MAPK1 P28482 2/20 1.00
HIF1A Q16665 2/20 1.00
TDP1 Q9NUW8 4/20 0.62
L3MBTL1 Q9Y468 4/20 0.62
LMNA P02545 2/20 0.62
THRB P10828 2/20 0.62
RECQL P46063 1/20 0.62
ATM Q13315 1/20 0.62
PTGS1 P23219 1/20 0.50
SLC6A2 P23975 1/20 0.50
PTGS2 P35354 1/20 0.50
HTR2B P41595 1/20 0.50
HPGD P15428 2/20 0.49
TP53 P04637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15476044 1.00 ALDH1A1 (1.00) ALDH1A1HSD17B10ALOX15TSHRALOX12
SCHEMBL31215174 1.00 ALDH1A1 (1.00) ALDH1A1HSD17B10ALOX15TSHRALOX12
SCHEMBL29251251 0.95 ALDH1A1 (0.90) ALDH1A1HSD17B10ALOX15TSHRALOX12
SCHEMBL6328763 0.95 ALDH1A1 (0.90) ALDH1A1HSD17B10ALOX15TSHRALOX12
SCHEMBL20996740 0.93 ALDH1A1 (0.87) ALDH1A1HSD17B10ALOX15TSHRALOX12
SCHEMBL18973334 0.92 ALDH1A1 (0.85) ALDH1A1HSD17B10ALOX15TSHRALOX12
SCHEMBL13996010 0.92 ALDH1A1 (0.85) ALDH1A1HSD17B10ALOX15TSHRALOX12
SCHEMBL9933293 0.92 ALDH1A1 (0.85) ALDH1A1HSD17B10ALOX15TSHRALOX12
SCHEMBL2255787 0.92 ALDH1A1 (0.85) ALDH1A1HSD17B10ALOX15TSHRALOX12
SCHEMBL9950267 0.92 ALDH1A1 (0.84) ALDH1A1HSD17B10ALOX15TSHRALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 19225 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120795417-B Application of waste diatomite white carbon black, sole material, preparation method and application thereof 上海唯革思生物科技有限公司 2026-05-19 CN claimed
CN-122037329-A Double-network crosslinked carcass rubber composition of cracked carbon black-bio-based liquid rubber and preparation method thereof 中策橡胶集团股份有限公司 2026-05-15 CN claimed
CN-122037330-A Rubber composition and preparation method thereof 青岛启雄腾达新材料有限公司 2026-05-15 CN claimed
WO-2026099687-A1 CROSS-LINKABLE ELASTOMERIC COMPOSITION AND TIRE PIRELLI TYRE S.P.A. (IT) 2026-05-15 WO claimed
EP-4739749-A1 RUBBER MULCH Heinige, Pavel (CZ) 2026-05-13 EP claimed
EP-4739717-A2 PREPARATION OF A HIGH REACTION TEMPERATURE DPAM HAVING IMPROVED STANDARD VISCOSITY AND WATER SOLUBILITY KEMIRA OYJ (FI) 2026-05-13 EP claimed
CN-122011611-A Composite rubber material for damping product and preparation method thereof 广东明凯新材料科技有限公司 2026-05-12 CN claimed
CN-122011573-A Rubber-plastic bicontinuous heterogeneous cross-linked dynamic vulcanized alloy, preparation method thereof and tire inner liner 道恩高材(北京)科技有限公司 2026-05-12 CN claimed
US-20260085215-A1 HIGH VISCOSITY ACRYLIC ADHESIVE DONGGUAN BOXIANG ELECTRONIC MAT CO LTD (CN) 2026-03-26 US claimed
US-12559398-B2 Systems and methods of removing toxic substances from water using vermifiltration PERCA, INC. (US) 2026-02-24 US claimed
US-4604439-A STABILIZERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1986-08-05 US claimed
US-4568711-A PARA-PHENYLENEDIAMINE, OPARA-DINITROSOARENE THE FIRESTONE TIRE & RUBBER COMPANY (US) 1986-02-04 US claimed
US-4559378-A GUAYLE RUBBER; SYNERGISTIC THE FIRESTONE TIRE & RUBBER COMPANY (US) 1985-12-17 US claimed
US-4517035-A Method of making a castable propellant HER MAJESTY THE QUEEN IN RIGHT OF CANADA, AS REPRESENTED BY THE MINISTER OF NATIONAL DEFENCE (CA) 1985-05-14 US claimed
US-4427468-A Curable propellant binding systems with bonding agent combination HER MAJESTY THE QUEEN IN RIGHT OF CANADA (CA) 1984-01-24 US claimed
US-4402859-A Process for producing diarylamine antioxidants in globular form SUMITOMO CHEMICAL CO., LTD. (JP) 1983-09-06 US claimed
US-4131622-A STEAM STRIPPING PENNWALT CORPORATION (US) 1978-12-26 US claimed
US-4051067-A Stabilization of unsaturated carboxylic acid esters with mixtures of polyalkyleneamines and arylenediamines MONSANTO COMPANY (US) 1977-09-27 US claimed
US-4016198-A Stabilization of unsaturated carboxylic acid esters with mixtures of polyalkylene-amines and arylenediamines MONSANTO COMPANY (US) 1977-04-05 US claimed
US-3975297-A Process of preparing free-flowing antiozonant blends THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-08-17 US claimed