Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 11/20 | 0.44 |
| ▸ | DRD2 | P14416 | 6/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1665509 | 0.89 | CCR1 (0.56) | CCR1NR1I2 | |
| Hydrochloric Acid SCHEMBL3949509 | 0.88 | CCR1 (0.55) | CCR1NR1I2 | |
| Hydrochloric Acid SCHEMBL3942169 | 0.80 | CCR1 (0.41) | CCR1HTR2AHTR2CHRH1 | |
| SCHEMBL3645828 | 0.76 | CCR1 (0.58) | CCR1NR1I2 | |
| SCHEMBL11903716 | 0.74 | CCR1 (0.61) | CCR1 | |
| SCHEMBL3943994 | 0.73 | CCR1 (0.57) | CCR1NR1I2 | |
| SCHEMBL2159774 | 0.73 | CCR1 (0.54) | CCR1NR1I2 | |
| SCHEMBL2159780 | 0.73 | CCR1 (0.54) | CCR1NR1I2 | |
| SCHEMBL2159776 | 0.73 | CCR1 (0.54) | CCR1NR1I2 | |
| SCHEMBL3941397 | 0.72 | DPP4 (0.37) | HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049486-A2 | PIPERIDINYL DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Bristol-Myers Squibb Company (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2007092681-A2 | PIPERIDINYL DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-16 | — | — | WO | disclosed |