Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.37 |
| ▸ | PLD1 | Q13393 | 3/20 | 0.33 |
| ▸ | PLD2 | O14939 | 2/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3947164 | 0.89 | CCR1 (0.38) | ADAMTS5KDM1ARCOR1HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL3945178 | 0.80 | SLC18A3 (0.41) | DPP4DPP8DPP9ADAMTS5HTR1A | |
| SCHEMBL3941362 | 0.78 | RORC (0.35) | PLD1PLD2 | |
| SCHEMBL3945236 | 0.72 | CCR1 (0.44) | HTR1AHTR2A | |
| SCHEMBL2159583 | 0.71 | DPP4 (0.53) | DPP4DPP8DPP9ADAMTS5 | |
| SCHEMBL2159587 | 0.71 | DPP4 (0.53) | DPP4DPP8DPP9ADAMTS5 | |
| Hydrochloric Acid SCHEMBL3940629 | 0.68 | DRD2 (0.51) | HTR1AHTR2A | |
| SCHEMBL10292301 | 0.68 | POLB (0.51) | DPP4DPP8DPP9ADAMTS5 | |
| SCHEMBL18030199 | 0.66 | CCR1 (0.47) | DPP4DPP8DPP9ADAMTS5 | |
| SCHEMBL3941357 | 0.65 | RORC (0.36) | DPP4DPP8DPP9ADAMTS5KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049486-A2 | PIPERIDINYL DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Bristol-Myers Squibb Company (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2007092681-A2 | PIPERIDINYL DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-16 | — | — | WO | disclosed |