Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTRN | P46939 | 11/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | AHR | P35869 | 1/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3953220 | 0.89 | UTRN (0.65) | UTRNCYP1A2AHRHDAC6MAPT | |
| Ezutromid SCHEMBL30791155 | 0.81 | UTRN (1.00) | UTRNCYP1A2AHRHDAC6MAPT | |
| Ezutromid SCHEMBL29376738 | 0.81 | UTRN (1.00) | UTRNCYP1A2AHRHDAC6MAPT | |
| Ezutromid SCHEMBL732212 | 0.81 | UTRN (1.00) | UTRNCYP1A2AHRHDAC6MAPT | |
| Ezutromid SCHEMBL31080435 | 0.81 | UTRN (1.00) | UTRNCYP1A2AHRHDAC6MAPT | |
| SCHEMBL13945649 | 0.80 | UTRN (0.58) | UTRNCYP1A2AHRHDAC6MAPT | |
| SCHEMBL3944431 | 0.78 | UTRN (0.77) | UTRNCYP1A2AHRHDAC6MAPT | |
| SCHEMBL12303235 | 0.76 | CYP1A2 (0.59) | CYP1A2 | |
| Ezutromid SCHEMBL3954452 | 0.75 | UTRN (0.84) | UTRNCYP1A2AHRHDAC6MAPT | |
| SCHEMBL2248143 | 0.75 | SMN1; SMN2 (0.72) | UTRNCYP1A2AHRHDAC6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009021750-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2009-02-19 | — | — | WO | disclosed |