Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3941781 | 0.98 | TP53 (0.47) | TP53PKML3MBTL1 | |
| SCHEMBL3947411 | 0.96 | MEN1 (0.50) | PKM | |
| SCHEMBL13942595 | 0.94 | TP53 (0.43) | TP53PKML3MBTL1 | |
| SCHEMBL3950554 | 0.94 | PKM (0.52) | TP53PKML3MBTL1 | |
| SCHEMBL3950668 | 0.94 | TP53 (0.43) | TP53PKML3MBTL1 | |
| SCHEMBL3944160 | 0.94 | PKM (0.54) | TP53PKML3MBTL1 | |
| SCHEMBL3952068 | 0.94 | MEN1 (0.48) | — | |
| SCHEMBL3951120 | 0.93 | TSHR (0.47) | TP53 | |
| SCHEMBL3945499 | 0.93 | TSHR (0.49) | — | |
| SCHEMBL3942037 | 0.93 | TP53 (0.45) | TP53PKML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |