Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTRN | P46939 | 9/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | AHR | P35869 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 9/20 | 0.47 |
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3947228 | 0.85 | UTRN (0.61) | UTRNCYP1A2AHRHDAC6ESR1 | |
| SCHEMBL3949434 | 0.80 | MAPT (0.58) | UTRNCYP1A2AHRHDAC6ESR1 | |
| SCHEMBL38658329 | 0.77 | ANPEP (0.51) | CYP1A2HDAC6MAPTTHRBSMN1; SMN2 | |
| SCHEMBL3894693 | 0.77 | ANPEP (0.51) | CYP1A2HDAC6MAPTTHRBSMN1; SMN2 | |
| SCHEMBL3952629 | 0.76 | ESR1 (0.85) | UTRNCYP1A2AHRHDAC6ESR1 | |
| SCHEMBL4227947 | 0.75 | UTRN (0.53) | UTRNCYP1A2AHRHDAC6ESR1 | |
| SCHEMBL3947253 | 0.74 | UTRN (0.77) | UTRNCYP1A2AHRHDAC6ESR1 | |
| SCHEMBL30727501 | 0.74 | NPC1 (0.62) | UTRNCYP1A2AHRHDAC6ESR1 | |
| SCHEMBL1913541 | 0.74 | NPC1 (0.62) | UTRNCYP1A2AHRHDAC6ESR1 | |
| SCHEMBL24881921 | 0.73 | SMN1; SMN2 (0.72) | UTRNCYP1A2AHRHDAC6ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009021750-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2009-02-19 | — | — | WO | disclosed |