Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 7/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38658329 | 1.00 | ANPEP (0.51) | ANPEPBACE1CNR2CYP3A4CYP2C9 | |
| SCHEMBL8638604 | 0.91 | CA2 (0.48) | ANPEPBACE1CNR2CYP3A4CYP2C9 | |
| SCHEMBL3968804 | 0.89 | CA2 (0.47) | ANPEPBACE1CNR2CYP3A4CYP2C9 | |
| SCHEMBL9770073 | 0.87 | BACE1 (0.56) | ANPEPBACE1CNR2CYP3A4CYP2C9 | |
| SCHEMBL29738643 | 0.87 | BACE1 (0.56) | ANPEPBACE1CNR2CYP3A4CYP2C9 | |
| SCHEMBL4995317 | 0.86 | BACE1 (0.54) | ANPEPBACE1CNR2CYP3A4CYP2C9 | |
| SCHEMBL11300596 | 0.82 | ACHE (0.49) | ANPEPCNR2CYP3A4CA12CA1 | |
| SCHEMBL9365248 | 0.82 | CA2 (0.46) | ANPEPBACE1CNR2CYP3A4CYP2C9 | |
| SCHEMBL23176846 | 0.81 | ALDH1A1 (0.65) | ANPEPBACE1CNR2CYP3A4CYP2C9 | |
| SCHEMBL11571563 | 0.81 | BACE1 (0.51) | ANPEPBACE1CNR2CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4252848-A2 | OXYSTEROLS AND METHODS OF USE THEREOF | Sage Therapeutics, Inc. (US) | 2023-10-04 | — | — | EP | disclosed |
| EP-3529257-B1 | OXYSTEROLS AND METHODS OF USE THEREOF | SAGE THERAPEUTICS INC (US) | 2023-05-10 | — | — | EP | disclosed |
| WO-2018075699-A1 | OXYSTEROLS AND METHODS OF USE THEREOF | SAGE THERAPEUTICS, INC. (US) | 2018-04-26 | — | — | WO | disclosed |
| EP-1831728-B1 | DISPLAYS HAVING A HIGH REFRACTIVE INDEX, DURABLE HARDCOAT LAYER | 3M INNOVATIVE PROPERTIES CO (US) | 2009-07-29 | — | — | EP | disclosed |
| US-7491441-B2 | High refractive index, durable hard coats | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-02-17 | — | — | US | disclosed |
| US-7491441-B2 | High refractive index, durable hard coats | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-02-17 | — | — | US | disclosed |
| US-7491441-B2 | High refractive index, durable hard coats | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-02-17 | — | — | US | disclosed |
| EP-1954732-A1 | COMPOSITIONS FOR BRIGHTNESS ENHANCING FILMS | General Electric Company (US) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007001811-A1 | COMPOSITIONS FOR BRIGHTNESS ENHANCING FILMS | GENERAL ELECTRIC COMPANY (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060293463-A1 | Compositions for brightness enhancing films | GENERAL ELECTRIC COMPANY | 2006-12-28 | — | — | US | disclosed |
| US-5283262-A | Antiinflammatory, antiallergens | GLAXO GROUP LIMITED (GB) | 1994-02-01 | — | — | US | disclosed |
| US-5281710-A | Antibiotics or antitumor agents | THE SCRIPPS RESEARCH INSTITUTE (US) | 1994-01-25 | — | — | US | disclosed |
| US-5276159-A | Antitumor | THE SCRIPPS RESEARCH INSTITUTE (US) | 1994-01-04 | — | — | US | disclosed |
| EP-0317206-B1 | PHENETHANOLAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1993-04-28 | — | — | EP | disclosed |
| EP-0512352-A2 | Substituted carboxylic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-11-11 | — | — | EP | disclosed |
| US-5109023-A | For treating asthma, chronic bronchits, gastrointestinal disorders, anticoagulant, antiinflammatory agent and antiallergens | GLAXO GROUP LIMITED (GB) | 1992-04-28 | — | — | US | disclosed |
| US-5099068-A | Antiulcer agents, beta-adrenoreceptors or bronchodilator agents for treatment of asthma | GLAXO GROUP LIMITED (GB) | 1992-03-24 | — | — | US | disclosed |
| WO-1992002522-A1 | DYNEMICIN ANALOGS: SYNTHESES, METHODS OF PREPARATION AND USE | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1992-02-20 | — | — | WO | disclosed |
| US-4997986-A | Respiratory system disorders | GLAXO GROUP LIMITED (GB) | 1991-03-05 | — | — | US | disclosed |
| EP-0317206-A2 | Phenethanolamine derivatives | GLAXO GROUP LIMITED (GB) | 1989-05-24 | — | — | EP | disclosed |