Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 12/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3947948 | 0.96 | TRPV4 (0.33) | TRPV4 | |
| Trifluoroacetic Acid SCHEMBL3948279 | 0.92 | TRPV4 (0.33) | TRPV4 | |
| SCHEMBL13032208 | 0.88 | TRPV4 (0.35) | TRPV4 | |
| SCHEMBL14931350 | 0.87 | TRPV4 (0.34) | TRPV4 | |
| SCHEMBL13032007 | 0.86 | TRPV4 (0.35) | TRPV4 | |
| SCHEMBL13024071 | 0.85 | EGLN1 (0.32) | TRPV4 | |
| Trifluoroacetic Acid SCHEMBL3484067 | 0.85 | — | — | |
| Trifluoroacetic Acid SCHEMBL3944485 | 0.84 | CACNA1B (0.35) | TRPV4 | |
| SCHEMBL13021453 | 0.84 | KMT2A (0.32) | — | |
| Trifluoroacetic Acid SCHEMBL3950645 | 0.83 | TRPV4 (0.34) | TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049200-A2 | NOVEL INHIBITORS OF BETA-LACTAMASE | MethylGene Inc. (CA) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008073142-A2 | NOVEL INHIBITORS OF BETA-LACTAMASE | MERCK & CO., INC. (US) | 2008-06-19 | — | — | WO | disclosed |