Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | BRS3 | P32247 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4010753 | 0.78 | DAO (0.40) | DAO | |
| SCHEMBL14723143 | 0.73 | DAO (0.39) | DAOGAAHRH3KMT2AMITF | |
| SCHEMBL17950142 | 0.70 | — | — | |
| SCHEMBL15728474 | 0.70 | KDM4C (0.38) | KMT2AMITFALDH1A1TP53 | |
| SCHEMBL14723507 | 0.69 | — | — | |
| SCHEMBL1706467 | 0.69 | — | — | |
| SCHEMBL9712799 | 0.68 | CYP1A2 (0.40) | GPR84 | |
| SCHEMBL28224387 | 0.68 | HRH4 (0.50) | DAOHRH3BRS3GPR84HRH4 | |
| Hydrochloric Acid SCHEMBL1707357 | 0.67 | NPC1 (0.54) | GAAKMT2AMITFALDH1A1TP53 | |
| SCHEMBL18367452 | 0.67 | CNR1 (0.41) | DAOBRS3KMT2AMITFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016410-A2 | CHEMICAL COMPOUNDS 831 | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | WO | disclosed |