SCHEMBL9712799

SCHEMBL9712799

CCC(CC)(CCCC1CCCCC1)c1cc(N)n[nH]1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.40
GPR84 Q9NQS5 1/20 0.32
NOS1 P29475 3/20 0.32
NOS2 P35228 3/20 0.32
SIGMAR1 Q99720 1/20 0.32
TLR7 Q9NYK1 1/20 0.32
CDK2 P24941 1/20 0.31
EHMT2 Q96KQ7 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
NOS3 P29474 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3946010 0.68 DAO (0.46) GPR84
SCHEMBL9713571 0.68 CYP1A2 (0.36) CYP1A2SIGMAR1TLR7NPSR1
Butylcyclohexane SCHEMBL28151648 0.62 CYP1A2 (0.90) CYP1A2NOS1NOS2SIGMAR1TLR7
Butylcyclohexane SCHEMBL27543884 0.62 CYP1A2 (0.90) CYP1A2NOS1NOS2SIGMAR1TLR7
SCHEMBL25389971 0.61 CYP1A2 (1.00) CYP1A2NOS1NOS2SIGMAR1TLR7
SCHEMBL7741430 0.61 CYP1A2 (1.00) CYP1A2NOS1NOS2SIGMAR1TLR7
SCHEMBL134772 0.61 CYP1A2 (1.00) CYP1A2NOS1NOS2SIGMAR1TLR7
Butylcyclohexane SCHEMBL2429501 0.61 CYP1A2 (1.00) CYP1A2NOS1NOS2SIGMAR1TLR7
SCHEMBL7732902 0.61 CYP1A2 (1.00) CYP1A2NOS1NOS2SIGMAR1TLR7
SCHEMBL133013 0.61 CYP1A2 (1.00) CYP1A2NOS1NOS2SIGMAR1TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5086184-A Herbicides DOWELANCO (US) 1992-02-04 US disclosed
US-4943634-A HERBICIDES ELI LILLY AND COMPANY (US) 1990-07-24 US disclosed
US-4801718-A HERBICIDES ELI LILLY AND COMPANY (US) 1989-01-31 US disclosed
US-4636243-A HERBICIDES ISOXAZOLES ELI LILLY AND COMPANY (US) 1987-01-13 US disclosed
US-4515625-A HERBICIDES ELI LILLY AND COMPANY (US) 1985-05-07 US disclosed
EP-0049071-B1 N-ARYLBENZAMIDE DERIVATIVES ELI LILLY AND COMPANY (US) 1984-12-19 EP disclosed
US-4416683-A HERBICIDES ELI LILLY AND COMPANY (US) 1983-11-22 US disclosed
EP-0049071-A1 N-arylbenzamide derivatives ELI LILLY AND COMPANY (US) 1982-04-07 EP disclosed