Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KRAS | P01116 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4197663 | 0.92 | RAB9A (0.58) | RAB9ANPC1HDAC1HDAC6ACKR3 | |
| SCHEMBL3943978 | 0.92 | RAB9A (0.58) | RAB9ANPC1HDAC1HDAC6ACKR3 | |
| SCHEMBL3944015 | 0.92 | RAB9A (0.58) | RAB9ANPC1HDAC1HDAC6ACKR3 | |
| SCHEMBL3942490 | 0.92 | RAB9A (0.58) | RAB9ANPC1HDAC1HDAC6ACKR3 | |
| SCHEMBL3941454 | 0.92 | RAB9A (0.58) | RAB9ANPC1HDAC1HDAC6ACKR3 | |
| SCHEMBL3941064 | 0.87 | RAB9A (0.57) | RAB9ANPC1HDAC1HDAC6ACKR3 | |
| SCHEMBL4198540 | 0.87 | RAB9A (0.57) | RAB9ANPC1HDAC1HDAC6ACKR3 | |
| SCHEMBL4033163 | 0.87 | RAB9A (0.57) | RAB9ANPC1HDAC1HDAC6ACKR3 | |
| SCHEMBL4200716 | 0.87 | RAB9A (0.52) | RAB9ANPC1HDAC1HDAC6ACKR3 | |
| SCHEMBL3941121 | 0.87 | RAB9A (0.52) | RAB9ANPC1HDAC1HDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | claimed |
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |