Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 6/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | EIF4E | P06730 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3885360 | 0.87 | AKR1C3 (0.43) | AKR1C3AKR1C2FFAR1MEN1ALDH1A1 | |
| SCHEMBL3954853 | 0.86 | AKR1C3 (0.46) | AKR1C3AKR1C2FFAR1FFAR4 | |
| SCHEMBL3946539 | 0.84 | AKR1C3 (0.44) | AKR1C3AKR1C2FFAR1MEN1ALDH1A1 | |
| SCHEMBL3946551 | 0.84 | AKR1C3 (0.44) | AKR1C3AKR1C2FFAR1MEN1ALDH1A1 | |
| SCHEMBL3882466 | 0.82 | CCNC (0.41) | AKR1C3AKR1C2MEN1ALDH1A1KMT2A | |
| SCHEMBL3885022 | 0.77 | FFAR1 (0.49) | AKR1C3AKR1C2FFAR1FFAR4 | |
| SCHEMBL3882257 | 0.74 | AKR1C3 (0.41) | AKR1C3AKR1C2FFAR1ALDH1A1 | |
| SCHEMBL3881043 | 0.74 | AKR1C3 (0.46) | AKR1C3AKR1C2FFAR1FFAR4 | |
| SCHEMBL3883628 | 0.73 | CCNC (0.45) | AKR1C3AKR1C2FFAR1MEN1ALDH1A1 | |
| SCHEMBL3954848 | 0.72 | AKR1C3 (0.47) | AKR1C3AKR1C2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |