Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TPH1 | P17752 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3882466 | 0.92 | CCNC (0.41) | AKR1C3AKR1C2UTS2RPPARGPPARA | |
| SCHEMBL3885022 | 0.91 | FFAR1 (0.49) | AKR1C3AKR1C2FFAR1FFAR4TPH1 | |
| SCHEMBL3946539 | 0.89 | AKR1C3 (0.44) | AKR1C3AKR1C2FFAR1UTS2RPTGDR2 | |
| SCHEMBL3946551 | 0.89 | AKR1C3 (0.44) | AKR1C3AKR1C2FFAR1UTS2RPTGDR2 | |
| SCHEMBL3946547 | 0.87 | AKR1C3 (0.43) | AKR1C3AKR1C2FFAR1FFAR4PTGDR2 | |
| SCHEMBL3881043 | 0.86 | AKR1C3 (0.46) | AKR1C3AKR1C2FFAR1FFAR4UTS2R | |
| SCHEMBL3882277 | 0.84 | FFAR4 (0.49) | FFAR1FFAR4PPARGPPARDPPARA | |
| SCHEMBL3883628 | 0.84 | CCNC (0.45) | AKR1C3AKR1C2FFAR1FFAR4MEN1 | |
| SCHEMBL3682322 | 0.80 | FFAR4 (0.47) | FFAR1FFAR4MEN1KMT2ACCNC | |
| SCHEMBL3882257 | 0.80 | AKR1C3 (0.41) | AKR1C3AKR1C2FFAR1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |