Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL475600 | 0.73 | KDM4E (0.46) | HCAR2KDM4EGAANPC1HSD17B10 | |
| SCHEMBL28300570 | 0.72 | CYP1A1 (0.52) | HCAR2KDM4EGAANPC1HSD17B10 | |
| SCHEMBL4169628 | 0.72 | NPC1 (0.49) | HCAR2KDM4EGAANPC1HSD17B10 | |
| SCHEMBL3232785 | 0.71 | HCAR2 (0.55) | HCAR2KDM4EGAANPC1HSD17B10 | |
| SCHEMBL4984247 | 0.71 | CDK2 (0.53) | KDM4EGAANPC1HSD17B10L3MBTL1 | |
| SCHEMBL22690047 | 0.70 | PDE10A (0.47) | HCAR2KDM4EGAANPC1HSD17B10 | |
| SCHEMBL30065933 | 0.69 | NPC1 (0.50) | HCAR2KDM4EGAANPC1HSD17B10 | |
| SCHEMBL3663141 | 0.69 | NPC1 (0.50) | HCAR2KDM4EGAANPC1HSD17B10 | |
| SCHEMBL15908507 | 0.68 | NPC1 (0.67) | HCAR2KDM4EGAANPC1HSD17B10 | |
| SCHEMBL18027880 | 0.67 | L3MBTL1 (0.59) | HCAR2KDM4EGAANPC1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016410-A2 | CHEMICAL COMPOUNDS 831 | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | WO | disclosed |