Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.46 |
| ▸ | PGR | P06401 | 4/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 10/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL291332 | 0.88 | NR3C1 (0.56) | NR3C1PGRNR3C2 | |
| SCHEMBL289779 | 0.79 | NR3C1 (0.54) | NR3C1PGRNR3C2 | |
| SCHEMBL290198 | 0.78 | NR3C1 (0.51) | NR3C1PGRNR3C2 | |
| SCHEMBL1634887 | 0.77 | NR3C1 (0.73) | NR3C1PGRNR3C2 | |
| SCHEMBL292540 | 0.77 | NR3C1 (0.56) | NR3C1PGRNR3C2 | |
| SCHEMBL292056 | 0.77 | NR3C1 (0.53) | NR3C1PGRNR3C2 | |
| SCHEMBL293410 | 0.77 | NR3C1 (0.54) | NR3C1PGRNR3C2 | |
| SCHEMBL293460 | 0.77 | NR3C1 (0.52) | NR3C1PGRNR3C2 | |
| SCHEMBL293459 | 0.76 | NR3C1 (0.53) | NR3C1PGRNR3C2 | |
| SCHEMBL293125 | 0.76 | NR3C1 (0.55) | NR3C1PGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051710-A2 | COMPOSITIONS AND METHODS FOR TREATING, REDUCING, AMELIORATING, OR ALLEVIATING POSTERIOR-SEGMENT OPHTHALMIC DISEASES | Bausch & Lomb Incorporated (US) | 2009-04-29 | — | — | EP | disclosed |
| WO-2008021729-A2 | COMPOSITIONS AND METHODS FOR TREATING, REDUCING, AMELIORATING, OR ALLEVIATING POSTERIOR-SEGMENT OPHTHALMIC DISEASES | BAUSCH & LOMB INCORPORATED (US) | 2008-02-21 | — | — | WO | disclosed |