Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | OXTR | P30559 | 1/20 | 0.30 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2993056 | 0.92 | PRKCA (0.37) | PRKCAMMP12NR1I2CYP3A4CYP2C9 | |
| SCHEMBL394673 | 0.90 | PRKCA (0.34) | PRKCAMMP12NR1I2CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL394360 | 0.88 | PRKCA (0.35) | PRKCAMMP12NR1I2CYP3A4CYP2C9 | |
| SCHEMBL2993061 | 0.88 | PRKCA (0.35) | PRKCAMMP12NR1I2CYP3A4CYP2C9 | |
| SCHEMBL394671 | 0.87 | PRKCA (0.35) | PRKCAMMP12NR1I2CYP3A4CYP2C9 | |
| SCHEMBL393462 | 0.83 | PRKCA (0.45) | PRKCAMMP12HTR2CSLC6A4NR1I2 | |
| SCHEMBL393583 | 0.81 | PRKCA (0.39) | PRKCAMMP12HTR2CSLC6A4CYP3A4 | |
| SCHEMBL14110707 | 0.75 | HTR2C (0.36) | PRKCAMMP12HTR2CSLC6A4 | |
| SCHEMBL5402256 | 0.75 | PRKCA (0.47) | PRKCAMMP12 | |
| SCHEMBL2907228 | 0.69 | PRKCA (0.50) | PRKCAMMP12NR1I2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101595-B2 | Antiviral indoles | Istituto di Ricerche di Biologia Molecolare P. Angletti SpA (IT) | 2012-01-24 | — | — | US | disclosed |