Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | GBA1 | P04062 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3957664 | 0.89 | RAD52 (0.38) | RAD52GNAO1POLBSMN1; SMN2CXCR4 | |
| SCHEMBL6921606 | 0.86 | RAD52 (0.46) | RAD52GNAO1POLBSMN1; SMN2CXCR4 | |
| SCHEMBL4836080 | 0.86 | RAD52 (0.46) | RAD52GNAO1POLBSMN1; SMN2CXCR4 | |
| SCHEMBL2238689 | 0.85 | GNAO1 (0.46) | GNAO1SMN1; SMN2GNAI3GNAI1ALDH1A1 | |
| SCHEMBL12843901 | 0.84 | GNAO1 (0.51) | RAD52GNAO1POLBSMN1; SMN2CXCR4 | |
| Hydrochloric Acid SCHEMBL6407048 | 0.83 | GNAO1 (0.49) | GNAO1SMN1; SMN2GNAI3GNAI1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27752774 | 0.82 | GNAO1 (0.54) | RAD52GNAO1POLBSMN1; SMN2CXCR4 | |
| SCHEMBL12397 | 0.82 | CYP1A2 (0.42) | SMN1; SMN2ALDH1A1DRD2HTR2ADRD3 | |
| SCHEMBL11181437 | 0.82 | RAD52 (0.52) | RAD52GNAO1POLBSMN1; SMN2CXCR4 | |
| SCHEMBL5745344 | 0.80 | GBA1 (0.45) | RAD52ALDH1A1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009024825-A1 | 2-PYRAZINYLBENZIMIDAZOLE DERIVATIVES AS RECEPTOR TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2009-02-26 | — | — | WO | disclosed |