Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 18/20 | 0.60 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GALK1 | P51570 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3947454 | 1.00 | TRPV1 (0.60) | TRPV1NPY5RKDM4EMAPTGALK1 | |
| SCHEMBL4023271 | 0.89 | TRPV1 (0.63) | TRPV1NPY5RKDM4EMAPTGALK1 | |
| SCHEMBL4020759 | 0.89 | TRPV1 (0.63) | TRPV1NPY5RKDM4EMAPTGALK1 | |
| SCHEMBL4023274 | 0.89 | TRPV1 (0.63) | TRPV1NPY5RKDM4EMAPTGALK1 | |
| SCHEMBL3937023 | 0.83 | TRPV1 (0.61) | TRPV1KDM4EMAPT | |
| SCHEMBL3937017 | 0.83 | TRPV1 (0.61) | TRPV1KDM4EMAPT | |
| SCHEMBL3947542 | 0.83 | TRPV1 (0.56) | TRPV1NPY5RKDM4EMAPTGALK1 | |
| SCHEMBL3947536 | 0.83 | TRPV1 (0.56) | TRPV1NPY5RKDM4EMAPTGALK1 | |
| SCHEMBL3946558 | 0.82 | TRPV1 (0.60) | TRPV1KDM4EMAPT | |
| SCHEMBL3946560 | 0.82 | TRPV1 (0.60) | TRPV1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203667-A1 | PENTADIENAMIDE DERIVATIVES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2009-08-13 | — | — | US | disclosed |
| US-20090203667-A1 | PENTADIENAMIDE DERIVATIVES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2009-08-13 | — | — | US | disclosed |
| US-20090203667-A1 | PENTADIENAMIDE DERIVATIVES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2009-08-13 | — | — | US | disclosed |
| EP-2050734-A1 | PENTADIENAMIDE DERIVATIVE | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203667-A1 | PENTADIENAMIDE DERIVATIVES | PRMT1, REN, NGLY1 | TRPV1 2741/4885NPY5R 279/4885KDM4E 212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.