Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.54 |
| ▸ | MAPT | P10636 | 10/20 | 0.54 |
| ▸ | GAA | P10253 | 8/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | CASP1 | P29466 | 3/20 | 0.44 |
| ▸ | CASP7 | P55210 | 2/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1719562 | 0.81 | ALDH1A1 (0.57) | BPTFALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL3947985 | 0.80 | BPTF (0.51) | BPTFALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL12882448 | 0.78 | BPTF (0.49) | BPTFALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL20254477 | 0.77 | PTPN5 (0.53) | BPTFALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL1719679 | 0.77 | ALDH1A1 (0.57) | BPTFALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL1207493 | 0.76 | ALDH1A1 (0.49) | BPTFALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL24862470 | 0.75 | BPTF (0.62) | BPTFALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL1208527 | 0.75 | BPTF (0.50) | BPTFALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL20254478 | 0.74 | MAPT (0.49) | BPTFALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL2648374 | 0.73 | ALDH1A1 (0.60) | BPTFALDH1A1MAPTGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051974-A1 | TETRAHYDROBENZOTHIOPHENE DERIVATIVES | 4SC AG (DE) | 2009-04-29 | — | — | EP | disclosed |
| WO-2008020045-A1 | TETRAHYDROBENZOTHIOPHENE DERIVATIVES | 4SC AG (DE) | 2008-02-21 | — | — | WO | disclosed |