⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3696791 | 0.94 | — | — | |
| SCHEMBL11700581 | 0.70 | — | — | |
| SCHEMBL671335 | 0.70 | — | — | |
| SCHEMBL21890920 | 0.69 | ACHE (0.37) | — | |
| SCHEMBL10177077 | 0.69 | — | — | |
| SCHEMBL28316808 | 0.69 | — | — | |
| SCHEMBL5933734 | 0.67 | — | — | |
| SCHEMBL2627461 | 0.67 | — | — | |
| SCHEMBL2627465 | 0.64 | — | — | |
| SCHEMBL18500517 | 0.64 | ACHE (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016269-A1 | WATER-SOLUBLE ETHYLIDENE PHOSPHATE PRODRUG OF PROPOFOL | OY FENNOPHARMA LTD (FI) | 2009-02-05 | — | — | WO | claimed |
| US-20250312361-A1 | FOSPROPOFOL METHODS AND COMPOSITIONS | EPALEX CORP (US) | 2025-10-09 | — | — | US | disclosed |
| US-12377110-B2 | Fospropofol methods and compositions | EPALEX CORPORATION (US) | 2025-08-05 | — | — | US | disclosed |
| EP-4288062-A1 | FOSPROPOFOL METHODS AND COMPOSITIONS | Epalex Corporation (US) | 2023-12-13 | — | — | EP | disclosed |
| US-20230277567-A1 | FOSPROPOFOL METHODS AND COMPOSITIONS | EPALEX CORPORATION | 2023-09-07 | — | — | US | disclosed |
| US-11628178-B2 | Fospropofol methods and compositions | EPALEX CORPORATION (US) | 2023-04-18 | — | — | US | disclosed |
| US-11478467-B2 | Targeted drug rescue with novel compositions, combinations, and methods thereof | Exciva GmbH (DE) | 2022-10-25 | — | — | US | disclosed |
| US-20220265686-A1 | FOSPROPOFOL METHODS AND COMPOSITIONS | EPALEX CORPORATION | 2022-08-25 | — | — | US | disclosed |
| WO-2022169520-A1 | FOSPROPOFOL METHODS AND COMPOSITIONS | EPALEX CORPORATION (US) | 2022-08-11 | — | — | WO | disclosed |
| US-20200261442-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | VEPACHEDU SREENIVASARAO (US) | 2020-08-20 | — | — | US | disclosed |
| EP-3618819-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | Exciva GmbH (DE) | 2020-03-11 | — | — | EP | disclosed |
| US-20200069674-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | Exciva GmbH (DE) | 2020-03-05 | — | — | US | disclosed |
| WO-2018204713-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | EXCIVA UG (HAFTUNGSBESCHRÄNKT) (DE) | 2018-11-08 | — | — | WO | disclosed |
| CN-103880754-A | Alkaline amino acid ester salt of propofol | XIZANG HAISCO PHARMACEUTICAL GROUP CO LTD | 2014-06-25 | — | — | CN | disclosed |
| WO-2009016269-A1 | WATER-SOLUBLE ETHYLIDENE PHOSPHATE PRODRUG OF PROPOFOL | OY FENNOPHARMA LTD (FI) | 2009-02-05 | — | — | WO | disclosed |
| WO-2009016269-A1 | WATER-SOLUBLE ETHYLIDENE PHOSPHATE PRODRUG OF PROPOFOL | OY FENNOPHARMA LTD (FI) | 2009-02-05 | — | — | WO | disclosed |