Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5679156 | 0.88 | NAAA (0.70) | NAAATSHRHTTALOX15HPGD | |
| SCHEMBL28472071 | 0.88 | NAAA (0.70) | NAAATSHRHTTALOX15HPGD | |
| SCHEMBL5674974 | 0.88 | NAAA (0.70) | NAAATSHRHTTALOX15HPGD | |
| SCHEMBL2159413 | 0.88 | NAAA (0.70) | NAAATSHRHTTALOX15HPGD | |
| SCHEMBL5674958 | 0.88 | NAAA (0.70) | NAAATSHRHTTALOX15HPGD | |
| SCHEMBL5674983 | 0.88 | NAAA (0.70) | NAAATSHRHTTALOX15HPGD | |
| SCHEMBL5679165 | 0.88 | NAAA (0.70) | NAAATSHRHTTALOX15HPGD | |
| SCHEMBL6065093 | 0.88 | NAAA (0.70) | NAAATSHRHTTALOX15HPGD | |
| SCHEMBL5678437 | 0.88 | NAAA (0.70) | NAAATSHRHTTALOX15HPGD | |
| SCHEMBL5940566 | 0.86 | TSHR (0.70) | NAAATSHRHTTALOX15HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1576093-A4 | 3-DEOXYGLUCOSONE AND SKIN | DYNAMIS THERAPEUTICS INC (US) | 2009-07-08 | — | — | EP | claimed |
| EP-1576093-A2 | 3-DEOXYGLUCOSONE AND SKIN | Dynamis Therapeutics, Inc. (US) | 2005-09-21 | — | — | EP | claimed |
| WO-2003089601-A2 | 3-DEOXYGLUCOSONE AND SKIN | DYNAMIS THERAPEUTICS, INC. (US) | 2003-10-30 | — | — | WO | claimed |