Ethylene

Ethylene

SCHEMBL3947801

C=C.C=C.CC(C)(C)c1cc(CC(=O)OCCOC(=O)Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc(C(C)(C)C)c1O

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.48
ALOX5 P09917 1/20 0.46
ALDH1A1 P00352 4/20 0.45
TSHR P16473 3/20 0.45
KMT2A Q03164 3/20 0.45
MAPK1 P28482 3/20 0.45
MEN1 O00255 2/20 0.45
CYP1A2 P05177 2/20 0.45
CYP3A4 P08684 2/20 0.45
BLM P54132 2/20 0.45
ATM Q13315 2/20 0.45
HIF1A Q16665 2/20 0.45
NPSR1 Q6W5P4 2/20 0.45
MAPT P10636 2/20 0.45
USP2 O75604 1/20 0.45
CYP2D6 P10635 1/20 0.45
LMNA P02545 3/20 0.45
GMNN O75496 1/20 0.44
GABBR2 O75899 1/20 0.44
TP53 P04637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL3949824 1.00 GAA (0.48) GAAALOX5ALDH1A1TSHRKMT2A
SCHEMBL206249 0.97 GAA (0.50) GAAALOX5ALDH1A1TSHRKMT2A
SCHEMBL11612616 0.92 GAA (0.47) GAAALOX5ALDH1A1TSHRKMT2A
SCHEMBL6926511 0.89 ALDH1A1 (0.44) GAAALOX5ALDH1A1TSHRKMT2A
SCHEMBL17014959 0.89 GAA (0.47) GAAALOX5ALDH1A1TSHRKMT2A
SCHEMBL8756260 0.88 GAA (0.46) GAAALOX5ALDH1A1TSHRKMT2A
SCHEMBL3949802 0.86 ALDH1A1 (0.42) GAAALOX5ALDH1A1TSHRKMT2A
Ethylene SCHEMBL4038426 0.86 GAA (0.57) GAAALOX5ALDH1A1TSHRKMT2A
Ethylene SCHEMBL1805199 0.86 GAA (0.57) GAAALOX5ALDH1A1TSHRKMT2A
Ethylene SCHEMBL6909288 0.86 GAA (0.57) GAAALOX5ALDH1A1TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2035470-A1 THERMOPLASTIC RESIN COMPOSITIONS SUITABLE FOR USE IN TRANSPARENT LAMINATES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-03-18 EP disclosed
WO-2007149082-A1 THERMOPLASTIC RESIN COMPOSITIONS SUITABLE FOR USE IN TRANSPARENT LAMINATES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-12-27 WO disclosed
US-20070289693-A1 Thermoplastic resin compositions suitable for use in transparent laminates E. I. DU PONT DE NEMOURS AND COMPANY 2007-12-20 US disclosed