Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5438409 | 1.00 | DPP4 (0.42) | DPP4LMNAALDH1A1MMP1MMP2 | |
| SCHEMBL5769336 | 0.85 | DPP4 (0.35) | DPP4LMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL5769339 | 0.85 | DPP4 (0.35) | DPP4LMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL15995187 | 0.84 | DPP4 (0.37) | DPP4LMNAALDH1A1MMP1MMP2 | |
| SCHEMBL19170142 | 0.81 | DPP4 (0.39) | DPP4LMNA | |
| SCHEMBL9873959 | 0.80 | CA12 (0.44) | DPP4LMNAALDH1A1SLC15A1CA12 | |
| SCHEMBL6201950 | 0.80 | CA12 (0.44) | DPP4LMNAALDH1A1SLC15A1CA12 | |
| SCHEMBL1619585 | 0.80 | DPP4 (0.47) | DPP4LMNAALDH1A1MMP1MMP2 | |
| SCHEMBL1619583 | 0.80 | DPP4 (0.47) | DPP4LMNAALDH1A1MMP1MMP2 | |
| Hydrochloric Acid SCHEMBL19136969 | 0.80 | DPP4 (0.38) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013628-A2 | METHODS OF EVALUATING PEPTIDE MIXTURES | Momenta Pharmaceuticals, Inc. (US) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007127977-A2 | METHODS OF EVALUATING PEPTIDE MIXTURES | MOMENTA PHARMACEUTICALS, INC. (US) | 2007-11-08 | — | — | WO | disclosed |