Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 9/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 9/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 9/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3943531 | 0.85 | EPHX1 (0.45) | EPHX1EPHX2FAAHS1PR4S1PR1 | |
| Trifluoroacetic Acid SCHEMBL3945536 | 0.78 | EPHX1 (0.42) | EPHX1EPHX2FAAHS1PR4S1PR1 | |
| Trifluoroacetic Acid SCHEMBL3948166 | 0.74 | EPHX1 (0.45) | EPHX1EPHX2FAAHS1PR4S1PR1 | |
| Iodide SCHEMBL3944404 | 0.74 | EPHX1 (0.44) | EPHX1EPHX2CA12CA1CA2 | |
| SCHEMBL15589848 | 0.69 | FAAH (0.38) | FAAHS1PR4S1PR1S1PR5S1PR3 | |
| Trifluoroacetic Acid SCHEMBL3943200 | 0.69 | EPHX2 (0.64) | EPHX1EPHX2FAAHS1PR1CA12 | |
| SCHEMBL978196 | 0.68 | FAAH (0.35) | EPHX1EPHX2FAAHS1PR4S1PR1 | |
| SCHEMBL980153 | 0.66 | FAAH (0.39) | FAAHS1PR4S1PR1S1PR5S1PR3 | |
| Trifluoroacetic Acid SCHEMBL3945551 | 0.64 | EPHX2 (0.61) | EPHX1EPHX2FAAHS1PR1CA12 | |
| SCHEMBL16249739 | 0.64 | HPGD (0.54) | EPHX1FAAHCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009015485-A1 | CYCLIC INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK (CA) | 2009-02-05 | — | — | WO | disclosed |