Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3948262 | 1.00 | NPC1 (0.48) | NPC1RAB9AMEN1LMNAMAPT | |
| SCHEMBL3948261 | 1.00 | NPC1 (0.48) | NPC1RAB9AMEN1LMNAMAPT | |
| SCHEMBL3945472 | 0.88 | MAOB (0.51) | NPC1RAB9AP2RX1CYP1A1CYP1B1 | |
| SCHEMBL3944870 | 0.88 | MAOB (0.51) | NPC1RAB9AP2RX1CYP1A1CYP1B1 | |
| SCHEMBL3944874 | 0.88 | MAOB (0.51) | NPC1RAB9AP2RX1CYP1A1CYP1B1 | |
| SCHEMBL3945561 | 0.87 | MAOB (0.43) | MEN1KMT2ACYP1A1CYP1B1MAOB | |
| SCHEMBL3945565 | 0.87 | MAOB (0.43) | MEN1KMT2ACYP1A1CYP1B1MAOB | |
| SCHEMBL3945568 | 0.87 | MAOB (0.43) | MEN1KMT2ACYP1A1CYP1B1MAOB | |
| SCHEMBL3938666 | 0.86 | CYP1A1 (0.52) | LMNAMAPTKMT2ACYP1A1CYP1B1 | |
| SCHEMBL3938660 | 0.86 | CYP1A1 (0.52) | LMNAMAPTKMT2ACYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203667-A1 | PENTADIENAMIDE DERIVATIVES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2009-08-13 | — | — | US | disclosed |
| EP-2050734-A1 | PENTADIENAMIDE DERIVATIVE | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203667-A1 | PENTADIENAMIDE DERIVATIVES | PRMT1, REN, NGLY1 | NPC1 3999/4885RAB9A 1128/4885MEN1 291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.