Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MGAM | O43451 | 1/20 | 0.52 |
| ▸ | SI | P14410 | 1/20 | 0.52 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2730412 | 0.97 | — | — | |
| Bromide SCHEMBL7748942 | 0.78 | GAA (0.50) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL28204489 | 0.75 | GAA (0.52) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL10400593 | 0.70 | — | — | |
| SCHEMBL10250397 | 0.70 | — | — | |
| Malonic Acid Diethyl Ester SCHEMBL456196 | 0.70 | GAA (0.88) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL4499955 | 0.70 | — | — | |
| Malonic Acid Diethyl Ester SCHEMBL1331824 | 0.69 | GAA (1.00) | GAAMGAMSIMGAM2ALDH1A1 | |
| Ethyl Propionate SCHEMBL1332690 | 0.69 | — | — | |
| Ethyl Propionate SCHEMBL4883389 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12344784-B2 | Stabilized perovskite quantum dot material | QUANTUM ADVANCED SOLUTIONS LIMITED (GB) | 2025-07-01 | — | — | US | claimed |
| US-20220064524-A1 | STABILIZED PEROVSKITE QUANTUM DOT MATERIAL | QUANTUM ADVANCED SOLUTIONS LIMITED (GB) | 2022-03-03 | — | — | US | claimed |
| CN-113149968-A | Compound serving as ketohexokinase inhibitor and application thereof | 广州博济医药生物技术股份有限公司 | 2021-07-23 | — | — | CN | claimed |
| US-9950983-B2 | Tricyclic compounds and process for preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2018-04-24 | — | — | US | claimed |
| US-20170233324-A1 | TRICYCLIC COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-08-17 | — | — | US | claimed |
| WO-2016013032-A1 | TRICYCLIC COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-01-28 | — | — | WO | claimed |
| US-8173584-B2 | Composition and method for treating semiconductor substrate surface | LASERWORT LTD (HK) | 2012-05-08 | — | — | US | claimed |
| US-20120083436-A1 | COMPOSITION AND METHOD FOR TREATING SEMICONDUCTOR SUBSTRATE SURFACE | LASERWORT LTD (HK) | 2012-04-05 | — | — | US | claimed |
| US-8101561-B2 | Composition and method for treating semiconductor substrate surface | LASERWORT LTD (HK) | 2012-01-24 | — | — | US | claimed |
| US-20110118165-A1 | COMPOSITION AND METHOD FOR TREATING SEMICONDUCTOR SUBSTRATE SURFACE | Lee, Wai Mun (US) | 2011-05-19 | — | — | US | claimed |
| EP-0877298-B1 | Coated xerographic photographic paper | XEROX CORP (US) | 2001-08-29 | — | — | EP | claimed |
| US-6210816-B1 | Translucent xerographic recording substrates | XEROX CORPORATION | 2001-04-03 | — | — | US | claimed |
| US-5908723-A | Recording sheets | XEROX CORPORATION (US) | 1999-06-01 | — | — | US | claimed |
| US-5846637-A | Coated xerographic photographic paper | XEROX CORPORATION (US) | 1998-12-08 | — | — | US | claimed |
| EP-0877298-A2 | Coated xerographic photographic paper | Xerox Corporation (US) | 1998-11-11 | — | — | EP | claimed |
| US-4154952-A | REACTING ALDEHYDES, METHYLENE COMPOUND, A SULFUR-CONTAINING HALIDE, AN INERT ORGANIC SOLVENT AND A STRONG BASE | SCHULTZ HARRY W | 1979-05-15 | — | — | US | claimed |
| WO-2026090317-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2026-04-30 | — | — | WO | disclosed |
| US-12435057-B2 | Triazole carboxylic acids as LPA antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-10-07 | — | — | US | disclosed |
| EP-0021160-A1 | Process for the preparation of trans-3,3-dimethyl-cyclopropane-1,2-dicarboxylic acid | BAYER AG (DE) | 1981-01-07 | — | — | EP | disclosed |
| US-4154952-A | REACTING ALDEHYDES, METHYLENE COMPOUND, A SULFUR-CONTAINING HALIDE, AN INERT ORGANIC SOLVENT AND A STRONG BASE | SCHULTZ HARRY W | 1979-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12435057-B2 | Triazole carboxylic acids as LPA antagonists | LPAR3, LPAR1, LPAR5 | GAA 1901/4885MGAM 3898/4885SI 1914/4885 |
| US-20170233324-A1 | TRICYCLIC COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | C1S, CYP11B1, NISCH | GAA 3822/4885MGAM 4181/4885SI 1842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.