Malonic Acid Diethyl Ester

Malonic Acid Diethyl Ester

SCHEMBL456196

CCCC.CCOC(=O)CC(=O)OCC

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.88
MGAM O43451 1/20 0.88
SI P14410 1/20 0.88
MGAM2 Q2M2H8 1/20 0.88
ALDH1A1 P00352 5/20 0.55
TRPA1 O75762 1/20 0.55
HSD17B10 Q99714 2/20 0.48
LMNA P02545 1/20 0.48
CYP1A2 P05177 1/20 0.46
ALOX15 P16050 2/20 0.46
SOAT1 P35610 1/20 0.46
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
TSHR P16473 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonic Acid Diethyl Ester SCHEMBL15388355 0.97 GAA (0.83) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL1864301 0.94 GAA (1.00) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL8636 0.94 GAA (1.00) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL1331187 0.94 GAA (1.00) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL1331824 0.94 GAA (1.00) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL1330550 0.94 GAA (1.00) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL8417856 0.91 GAA (0.94) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL11027431 0.91 GAA (0.94) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL3670061 0.91 GAA (0.94) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL4334303 0.91 GAA (0.94) GAAMGAMSIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 460 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119390574-A 1, 4-Fullerene C60Derivatives and process for preparing the same 吉林化工学院 2025-02-07 CN claimed
US-12113460-B2 Electrostatic machine system and method of operation C-Motive Technologies, Inc. (US) 2024-10-08 US claimed
CN-118620520-A Polyamide imide varnish cured at low temperature and preparation method and application thereof 宁波博雅聚力新材料科技有限公司 2024-09-10 CN claimed
EP-4388138-A1 CONDENSATES, A PROCESS FOR THEIR MANUFACTURE AND THEIR USE AS RE-TANNING AGENTS Stahl International B.V. (NL) 2024-06-26 EP claimed
US-11742779-B2 Electrostatic motor having fluid management features C-Motive Technologies, Inc. (US) 2023-08-29 US claimed
CN-112354566-B Barbituric acid-polymetallic oxygen cluster hybrid and preparation method thereof 中北大学 2023-04-21 CN claimed
CN-112570025-B Barbituric acid modified polyoxometalate hybrid and preparation method thereof 中北大学 2023-04-21 CN claimed
WO-2023022595-A1 CONDENSATES, A PROCESS FOR THEIR MANUFACTURE AND THEIR USE AS RE-TANNING AGENTS STAHL INTERNATIONAL B.V. (NL) 2023-02-23 WO claimed
EP-4085521-A1 ELECTROSTATIC MOTOR HAVING FLUID MANAGEMENT FEATURES C-Motive Technologies Inc. (US) 2022-11-09 EP claimed
EP-4085520-A1 ELECTROSTATIC MOTOR C-Motive Technologies Inc. (US) 2022-11-09 EP claimed
CN-104513330-A Catalyst system used in olefin polymerization and application thereof CHINA PETROLEUM & CHEMICAL 2015-04-15 CN claimed
CN-104513332-A Catalyst system used in olefin polymerization and application thereof CHINA PETROLEUM & CHEMICAL 2015-04-15 CN claimed
US-6415614-B1 CONTROLLING VAPOR PRESSURE OF MIXTURE VISTEON GLOBAL TECHNOLOGIES, INC. 2002-07-09 US claimed
CN-1075103-C Polyurethane adhesives/sealant composition, precursor and preparation process thereof AOBO ADHESIVE CHEMICAL CO LTD (CN) 2001-11-21 CN claimed
EP-0674233-B1 Recording sheets XEROX CORP (US) 2000-05-24 EP claimed
CN-1248606-A Polyurethane adhesives/sealant composition, precursor and preparation process thereof AOBO ADHEIVE CHEMICAL CO LTD S (CN) 2000-03-29 CN claimed
US-5928765-A Recording sheets XEROX CORPORATION (US) 1999-07-27 US claimed
CN-1166177-A Primer comspn. NIPPON ARC CO LTD (JP) 1997-11-26 CN claimed
US-5583188-A USING TITANIUM, ORGANOALUMINUM, NITROGEN OR OXYGEN HETEROCYCLE CONTAINING CATALYST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-12-10 US claimed
EP-0674233-A2 Recording sheets XEROX CORPORATION (US) 1995-09-27 EP claimed