Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 15/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 14/20 | 0.42 |
| ▸ | PGR | P06401 | 13/20 | 0.42 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14157412 | 0.80 | NR3C1 (0.39) | NR3C1NR3C2PGRRPS6KA5 | |
| SCHEMBL292128 | 0.78 | NR3C1 (0.56) | NR3C1NR3C2PGR | |
| SCHEMBL1932724 | 0.76 | NR3C1 (0.46) | NR3C1NR3C2PGRAR | |
| SCHEMBL4214200 | 0.76 | NR3C1 (0.48) | NR3C1NR3C2PGR | |
| SCHEMBL289458 | 0.75 | NR3C1 (0.43) | NR3C1NR3C2PGRRPS6KA5 | |
| SCHEMBL1932409 | 0.74 | NR3C1 (0.43) | NR3C1NR3C2PGRAR | |
| SCHEMBL3686538 | 0.72 | NR3C1 (0.61) | NR3C1NR3C2PGR | |
| SCHEMBL15756277 | 0.69 | NR3C1 (0.63) | NR3C1NR3C2PGR | |
| SCHEMBL6384931 | 0.67 | NR3C1 (0.54) | NR3C1NR3C2PGR | |
| SCHEMBL5078470 | 0.67 | NR3C1 (0.53) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012170175-A1 | COMPOSITIONS AND METHODS FOR TREATING, CONTROLLING, REDUCING, OR AMELIORATING INFLAMMATORY PAIN | BAUSCH & LOMB INCORPORATED (US) | 2012-12-13 | — | — | WO | disclosed |
| EP-2051710-A2 | COMPOSITIONS AND METHODS FOR TREATING, REDUCING, AMELIORATING, OR ALLEVIATING POSTERIOR-SEGMENT OPHTHALMIC DISEASES | Bausch & Lomb Incorporated (US) | 2009-04-29 | — | — | EP | disclosed |
| WO-2008021729-A2 | COMPOSITIONS AND METHODS FOR TREATING, REDUCING, AMELIORATING, OR ALLEVIATING POSTERIOR-SEGMENT OPHTHALMIC DISEASES | BAUSCH & LOMB INCORPORATED (US) | 2008-02-21 | — | — | WO | disclosed |