SCHEMBL3948403

SCHEMBL3948403

CCN(CC)NC(O)=S.NC(O)=S

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2650614 0.98 KDM4E (0.33) KDM4EL3MBTL1
SCHEMBL2765694 0.98 KDM4E (0.33) KDM4EL3MBTL1
SCHEMBL29053914 0.98 KDM4E (0.33) KDM4EL3MBTL1
Water SCHEMBL2650094 0.95 KDM4E (0.32) KDM4EL3MBTL1
SCHEMBL8847739 0.92
SCHEMBL28344461 0.90 KDM4E (0.36) KDM4EL3MBTL1
SCHEMBL28156197 0.90 KDM4E (0.36) KDM4EL3MBTL1
SCHEMBL28349781 0.79 CA12 (0.41)
SCHEMBL17755490 0.79
SCHEMBL29269025 0.70 ALDH1A1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108543077-B Mesoporous silica nanoparticle of disulfiram monomer and preparation method and application thereof 武汉迈德森医药科技股份有限公司 2021-04-30 CN claimed
CN-110683975-A Synthesis method of dialkyl amino alkyl dithioformate 成都理工大学 2020-01-14 CN claimed
CN-108543077-B Mesoporous silica nanoparticle of disulfiram monomer and preparation method and application thereof 武汉迈德森医药科技股份有限公司 2021-04-30 CN disclosed
CN-110683975-B Synthesis method of dialkyl amino alkyl dithioformate 成都理工大学 2021-04-09 CN disclosed
CN-107226599-B Recycling treatment method of iron-containing heavy metal sludge 环境保护部南京环境科学研究所 2020-02-21 CN disclosed
CN-110683975-A Synthesis method of dialkyl amino alkyl dithioformate 成都理工大学 2020-01-14 CN disclosed
EP-2052034-B1 THIOL DERIVATIVE DYES BASF SE (DE) 2016-06-08 EP disclosed
EP-2052034-A2 THIOL DERIVATIVE DYES Ciba Holding Inc. (CH) 2009-04-29 EP disclosed
WO-2008019977-A2 THIOL DERIVATIVE DYES CIBA HOLDING INC. (CH) 2008-02-21 WO disclosed