Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TYR | P14679 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 12/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.55 |
| ▸ | ACR | P10323 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3954838 | 0.91 | CNR2 (0.64) | TSHRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL7755450 | 0.88 | CNR2 (0.61) | TSHRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL7754579 | 0.88 | CNR2 (0.61) | TSHRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL7751126 | 0.88 | CNR2 (0.61) | TSHRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL7755667 | 0.88 | CNR2 (0.61) | TSHRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL3952691 | 0.84 | CNR2 (0.57) | TSHRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL3035441 | 0.84 | HTR1A (0.59) | TSHRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL6022639 | 0.84 | TYR (0.64) | TSHRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL7755433 | 0.84 | TYR (0.50) | TSHRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL3032659 | 0.82 | MEN1 (0.55) | TSHRMEN1TP53CYP3A4ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009021590-A1 | TYROSINASE INHIBITORS | MERCK PATENT GMBH (DE) | 2009-02-19 | — | — | WO | claimed |
| WO-2009021590-A1 | TYROSINASE INHIBITORS | MERCK PATENT GMBH (DE) | 2009-02-19 | — | — | WO | disclosed |
| WO-2009021590-A1 | TYROSINASE INHIBITORS | MERCK PATENT GMBH (DE) | 2009-02-19 | — | — | WO | disclosed |