Adenosine Phosphate

Adenosine Phosphate

SCHEMBL3948645

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O.O=P(O)(O)O

nearest known ligand 0.98

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Adenosine Phosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 known ✓ P07550 1/20 0.98
KCNH2 known ✓ Q12809 1/20 0.98
P2RY1 P47900 5/20 0.98
P2RY2 P41231 3/20 0.98
SRC P12931 2/20 0.98
SMN1; SMN2 Q16637 2/20 0.98
TRPM2 O94759 2/20 0.98
TAS1R3 Q7RTX0 2/20 0.98
TAS1R1 Q7RTX1 2/20 0.98
DNPH1 O43598 1/20 0.98
PRKAB2 O43741 1/20 0.98
LDHA P00338 1/20 0.98
FBP1 P09467 1/20 0.98
ADORA1 P30542 1/20 0.98
PRKAG1 P54619 1/20 0.98
PRKAA2 P54646 1/20 0.98
PDE4D Q08499 1/20 0.98
PRKAA1 Q13131 1/20 0.98
PDE3A Q14432 1/20 0.98
P2RY11 Q96G91 1/20 0.98

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenosine Phosphate SCHEMBL27502312 1.00 P2RY1 (0.98) P2RY1P2RY2SRCSMN1; SMN2TRPM2
Adenosine Phosphate SCHEMBL30012158 1.00 P2RY1 (0.98) P2RY1P2RY2SRCSMN1; SMN2TRPM2
Adenosine Phosphate SCHEMBL14478782 0.99 P2RY1 (1.00) P2RY1P2RY2SRCSMN1; SMN2TRPM2
Adenosine Phosphate SCHEMBL144997 0.99 P2RY1 (1.00) P2RY1P2RY2SRCSMN1; SMN2TRPM2
Adenosine Phosphate SCHEMBL13374692 0.99 P2RY1 (1.00) P2RY1P2RY2SRCSMN1; SMN2TRPM2
Adenosine Phosphate SCHEMBL19420134 0.99 P2RY1 (1.00) P2RY1P2RY2SRCSMN1; SMN2TRPM2
Adenosine Phosphate SCHEMBL1338615 0.99 P2RY1 (1.00) P2RY1P2RY2SRCSMN1; SMN2TRPM2
Adenosine Phosphate SCHEMBL20277555 0.99 P2RY1 (1.00) P2RY1P2RY2SRCSMN1; SMN2TRPM2
Adenosine Phosphate SCHEMBL132458 0.99 P2RY1 (1.00) P2RY1P2RY2SRCSMN1; SMN2TRPM2
Adenosine Phosphate SCHEMBL13170051 0.99 P2RY1 (1.00) P2RY1P2RY2SRCSMN1; SMN2TRPM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116651412-A Preparation method and application of Pickering emulsion interface-induced finite-domain polymeric imprinting adsorbent 江苏大学 2023-08-29 CN claimed
WO-2022213447-A1 PREPARATION METHOD FOR VIDARABINE MONOPHOSPHATE FREEZE-DRIED POWDER INJECTION 海南锦瑞制药有限公司 2022-10-13 WO claimed
CN-114045275-A Monophosphoryl adenylate enzyme and preparation method and application thereof 云南省烟草农业科学研究院 2022-02-15 CN claimed
WO-2021252904-A1 RIBONUCLEOPROTEIN APPROACH TO BOOST THE STING SIGNALING FOR CANCER IMMUNOTHERAPY MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-12-16 WO claimed
CN-112672763-A Compositions and methods for metal-containing formulations capable of modulating immune responses 密执安大学评议会 2021-04-16 CN claimed
CN-101107356-B Enzymatic synthesis method of 3 '-adenosine phosphate-5' -phosphosulfate YAMASA CORP 2012-06-13 CN claimed
CN-101573447-A Methionine synthases with reduced product inhibition BASF SE (DE) 2009-11-04 CN claimed
CN-110099905-B Substituted pyrazoloazepin-8-ones and their use as phosphodiesterase inhibitors 联合疗法公司 2024-06-14 CN disclosed
CN-110088108-B Substituted pyrazoloazepin-4-ones and their use as phosphodiesterase inhibitors 联合疗法公司 2024-06-14 CN disclosed
WO-2024097804-A1 COMBINATION OF A TYROSINE KINASE INHIBITOR AND A PRO-INFLAMMATORY AGENT FOR TREATING CANCER MDX MANAGEMENT LLC (US) 2024-05-10 WO disclosed
CN-114045275-B Adenosine monophosphate enzyme and preparation method and application thereof 云南省烟草农业科学研究院 2024-05-07 CN disclosed
CN-111712503-B Substituted tetrahydropyran dihydro-thienopyrimidines and their use as phosphodiesterase inhibitors 联合疗法公司 2024-04-09 CN disclosed
CN-112135791-B Organically modified mineral particles, method for the production and use thereof 禾大国际股份公开有限公司 2024-01-26 CN disclosed
US-5612060-A Enhancement of transplant graft survival through nutritional immunomodulation and immunosuppressive therapy NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 1997-03-18 US disclosed
WO-1996000585-A1 DIPHOSPHATE OR TRIPHOSPHATE ANALOGUE CONJUGATES COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1996-01-11 WO disclosed
WO-1994004194-A1 NUCLEIC ACID RECOGNITION AND TRANSPORT MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1994-03-03 WO disclosed
US-5279664-A Mixture of an amine compound, sodium and potassium hydroxide and chelate compound ANGUS CHEMICAL COMPANY (US) 1994-01-18 US disclosed
WO-1993012050-A1 DISPERSING AGENTS FOR COMMINUTED SOLIDS ANGUS CHEMICAL COMPANY (US) 1993-06-24 WO disclosed
WO-1992020813-A1 ASSAYS FOR FACTORS AFFECTING CIRCULARIZATION OF DNA, ASSAYS FOR FACTORS AFFECTING DNA INTEGRATION, FACTORS, AND USES THEREOF DANA FARBER CANCER INSTITUTE (US) 1992-11-26 WO disclosed
US-4345945-A IN WATER, USING A MONO-, DE- OR TRI-SALT OF AN ALKANOLAMINE AND AN INORGANIC ACID OF PHOSPHORUS INTERNATIONAL MINERALS & CHEMICAL CORP. (US) 1982-08-24 US disclosed