Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3948704 | 0.86 | CYP3A4 (0.44) | FAAHMGLLCYP3A4TRPM8ALDH1A1 | |
| SCHEMBL3951209 | 0.85 | CYP3A4 (0.51) | FAAHMGLLCYP3A4CALM1TRPA1 | |
| SCHEMBL3941640 | 0.85 | NPC1 (0.53) | FAAHMGLLCYP3A4CALM1ALDH1A1 | |
| SCHEMBL3939955 | 0.83 | CYP3A4 (0.47) | FAAHMGLLCYP3A4TRPA1TRPM8 | |
| SCHEMBL3947205 | 0.79 | FFAR1 (0.58) | CYP3A4FFAR1FFAR4ALDH1A1MAPT | |
| SCHEMBL3941686 | 0.79 | RAB9A (0.52) | FFAR1FFAR4MCHR1MAPTNPC1 | |
| SCHEMBL3951977 | 0.78 | FFAR1 (0.46) | FFAR1FFAR4HDAC6 | |
| SCHEMBL3950320 | 0.77 | FFAR1 (0.45) | FFAR1FFAR4 | |
| SCHEMBL29067208 | 0.76 | CYP3A4 (0.74) | FAAHMGLLCYP3A4ALDH1A1MAPT | |
| SCHEMBL3943298 | 0.76 | FFAR1 (0.43) | CYP3A4FFAR1FFAR4ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |