Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.34 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 4/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3941108 | 1.00 | EPHX1 (0.34) | EPHX1CHRM2CHRM4CHRM3CHRM1 | |
| SCHEMBL3938062 | 1.00 | EPHX1 (0.34) | EPHX1CHRM2CHRM4CHRM3CHRM1 | |
| SCHEMBL1078770 | 0.88 | SERPINE1 (0.42) | EPHX1CHRM2CHRM4CHRM3CHRM1 | |
| SCHEMBL3945588 | 0.84 | DPP4 (0.34) | CHRM2CHRM4CHRM3CHRM1SERPINE1 | |
| SCHEMBL3938231 | 0.84 | DPP4 (0.34) | CHRM2CHRM4CHRM3CHRM1SERPINE1 | |
| SCHEMBL698655 | 0.83 | — | — | |
| SCHEMBL10344338 | 0.83 | EPHX1 (0.45) | EPHX1DPP4DPP7MMP1MMP2 | |
| SCHEMBL1078866 | 0.82 | EPHX1 (0.47) | EPHX1SERPINE1TSHRCYP3A4CYP2C19 | |
| SCHEMBL1081348 | 0.81 | SERPINE1 (0.38) | EPHX1CHRM2CHRM4CHRM3CHRM1 | |
| SCHEMBL2327031 | 0.80 | CHRM2 (0.43) | EPHX1CHRM2CHRM4CHRM3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805316-B1 | PROCESS FOR THE PREPARATION OF THE ENANTIOMERIC FORMS OF CIS-3-HYDROXYCYCLOHEXANE CARBOXYLIC ACID DERIVATIVES EMPLOYING HYDROLASES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-04-15 | — | — | EP | disclosed |