Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3945588 | 1.00 | DPP4 (0.34) | DPP4DPP7CHRM2CHRM4CHRM1 | |
| SCHEMBL1081363 | 0.89 | SERPINE1 (0.39) | DPP4DPP7CHRM2CHRM4CHRM1 | |
| SCHEMBL1077758 | 0.84 | SERPINE1 (0.36) | DPP4DPP7CHRM2CHRM4CHRM3 | |
| SCHEMBL3941108 | 0.84 | EPHX1 (0.34) | DPP4DPP7CHRM2CHRM4CHRM1 | |
| SCHEMBL3938062 | 0.84 | EPHX1 (0.34) | DPP4DPP7CHRM2CHRM4CHRM1 | |
| SCHEMBL3948977 | 0.84 | EPHX1 (0.34) | DPP4DPP7CHRM2CHRM4CHRM1 | |
| SCHEMBL28690325 | 0.83 | RAB9A (0.37) | DPP4DPP7SERPINE1TSHR | |
| SCHEMBL19857074 | 0.83 | RAB9A (0.37) | DPP4DPP7SERPINE1TSHR | |
| SCHEMBL3938214 | 0.83 | TSHR (0.39) | DPP4DPP7CHRM2CHRM4CHRM1 | |
| SCHEMBL1080567 | 0.83 | EPHX1 (0.42) | SERPINE1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805316-B1 | PROCESS FOR THE PREPARATION OF THE ENANTIOMERIC FORMS OF CIS-3-HYDROXYCYCLOHEXANE CARBOXYLIC ACID DERIVATIVES EMPLOYING HYDROLASES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-04-15 | — | — | EP | disclosed |
| EP-1805316-A2 | METHOD FOR PRODUCING THE ENANTIOMER FORMS OF CIS-CONFIGURED 3-HYDROXYCYCLOHEXANE CARBOXYLIC ACID DERIVATIVES USING HYDROLASES | Sanofi-Aventis Deutschland GmbH (DE) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006015716-A2 | METHOD FOR PRODUCING THE ENANTIOMER FORMS OF CIS-CONFIGURED 3-HYDROXYCYCLOHEXANE CARBOXYLIC ACID DERIVATIVES USING HYDROLASES | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2006-02-16 | — | — | WO | disclosed |