Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 16/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3949010 | 0.93 | TRPV4 (0.37) | TRPV4 | |
| SCHEMBL13032041 | 0.89 | TRPV4 (0.38) | TRPV4 | |
| SCHEMBL14931384 | 0.89 | TRPV4 (0.36) | TRPV4 | |
| SCHEMBL14931224 | 0.89 | TRPV4 (0.36) | TRPV4 | |
| Trifluoroacetic Acid SCHEMBL3942311 | 0.88 | TRPV4 (0.34) | TRPV4 | |
| SCHEMBL14931399 | 0.88 | — | — | |
| Trifluoroacetic Acid SCHEMBL3950588 | 0.85 | TRPV4 (0.35) | TRPV4 | |
| SCHEMBL13032069 | 0.84 | TRPV4 (0.35) | TRPV4 | |
| SCHEMBL14931180 | 0.82 | TRPV4 (0.36) | TRPV4 | |
| SCHEMBL14931223 | 0.82 | TRPV4 (0.36) | TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8440643-B2 | Inhibitors of beta-lactamase | METHYLGENE INC. (CA) | 2013-05-14 | — | — | US | claimed |
| EP-2049200-A2 | NOVEL INHIBITORS OF BETA-LACTAMASE | MethylGene Inc. (CA) | 2009-04-22 | — | — | EP | claimed |
| WO-2008073142-A2 | NOVEL INHIBITORS OF BETA-LACTAMASE | MERCK & CO., INC. (US) | 2008-06-19 | — | — | WO | claimed |
| US-8440643-B2 | Inhibitors of beta-lactamase | METHYLGENE INC. (CA) | 2013-05-14 | — | — | US | disclosed |