Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7283109 | 0.88 | ALDH1A1 (0.57) | GAAALDH1A1ALOX5OR51E2GFER | |
| SCHEMBL7398838 | 0.86 | GAA (0.59) | GAAALDH1A1ALOX5OR51E2LMNA | |
| Hydrochloric Acid SCHEMBL6986396 | 0.85 | CYP4F2 (0.54) | GAAALDH1A1ALOX5OR51E2LMNA | |
| SCHEMBL3940302 | 0.85 | KMT2A (0.59) | ALDH1A1ALOX5OR51E2MEN1KMT2A | |
| SCHEMBL18046156 | 0.85 | ALDH1A1 (0.53) | GAAALDH1A1ALOX5OR51E2LMNA | |
| SCHEMBL7247237 | 0.84 | ALDH1A1 (0.69) | GAAALDH1A1LMNAHTTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6983661 | 0.83 | ALDH1A1 (0.67) | GAAALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL11216725 | 0.83 | ALDH1A1 (0.71) | GAAALDH1A1ALOX5OR51E2GFER | |
| SCHEMBL28287006 | 0.83 | CYP19A1 (0.65) | GAAALOX5OR51E2LMNAMEN1 | |
| SCHEMBL22187923 | 0.81 | ALDH1A1 (0.49) | GAAALDH1A1ALOX5OR51E2GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1285908-B9 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2009-04-22 | — | — | EP | disclosed |
| EP-1285908-B1 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2008-09-10 | — | — | EP | disclosed |
| US-7049342-B2 | Substituted phenylpropionic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2006-05-23 | — | — | US | disclosed |
| US-20030187068-A1 | Substituted phenylpropionic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1285908-A1 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-02-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187068-A1 | Substituted phenylpropionic acid derivatives | PPARA, PPARG, PPARD | GAA 2420/4885ALDH1A1 429/4885ALOX5 1110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.