Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 14/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.62 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.62 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.58 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.58 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3947025 | 1.00 | ADORA1 (0.62) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 | |
| SCHEMBL5034539 | 1.00 | ADORA1 (0.62) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 | |
| SCHEMBL5132305 | 1.00 | ADORA1 (0.62) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 | |
| SCHEMBL3955602 | 0.92 | ADORA1 (0.63) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 | |
| SCHEMBL5397271 | 0.91 | ADORA3 (0.60) | ADORA1ADORA3ADORA2AADORA2BSLC29A1 | |
| SCHEMBL3956079 | 0.91 | ADORA1 (0.60) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 | |
| SCHEMBL3946580 | 0.89 | ADORA1 (0.51) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 | |
| SCHEMBL3948665 | 0.89 | ADORA1 (0.49) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 | |
| SCHEMBL3952671 | 0.88 | ADORA1 (0.61) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 | |
| SCHEMBL3952324 | 0.87 | ADORA1 (0.49) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156544-A1 | A1 ADENOSINE RECEPTOR AGONISTS | ELZEIN ELFATIH | 2009-06-18 | — | — | US | disclosed |
| US-7514417-B2 | A1 adenosine receptor agonists | CV THERAPEUTICS, INC. (US) | 2009-04-07 | — | — | US | disclosed |
| EP-1881991-A1 | A1 ADENOSINE RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2008-01-30 | — | — | EP | disclosed |
| US-20060281705-A1 | A1 adenosine receptor agonists | CV THERAPEUTICS, INC. | 2006-12-14 | — | — | US | disclosed |
| WO-2006125211-A1 | A1 ADENOSINE RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2006-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156544-A1 | A1 ADENOSINE RECEPTOR AGONISTS | ADORA1, ADORA2A, ADORA3 | ADORA1 1/4885ADORA3 3/4885ADORA2A 2/4885 |
| US-20060281705-A1 | A1 adenosine receptor agonists | ADORA1, ADORA2A, ADORA3 | ADORA1 1/4885ADORA3 3/4885ADORA2A 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.