Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.95 |
| ▸ | CA2 | P00918 | 4/20 | 0.95 |
| ▸ | POLB | P06746 | 1/20 | 0.95 |
| ▸ | TYR | P14679 | 1/20 | 0.95 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HPN | P05981 | 1/20 | 0.54 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butylated Hydroxytoluene SCHEMBL453824 | 0.97 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL3950 | 0.97 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL7075597 | 0.95 | SMN1; SMN2 (0.95) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL20660368 | 0.95 | SMN1; SMN2 (0.95) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL31314972 | 0.95 | SMN1; SMN2 (0.95) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL864242 | 0.95 | SMN1; SMN2 (0.95) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL11859223 | 0.95 | SMN1; SMN2 (0.95) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL9343306 | 0.95 | SMN1; SMN2 (0.95) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL9343307 | 0.95 | SMN1; SMN2 (0.95) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL11857289 | 0.95 | SMN1; SMN2 (0.95) | SMN1; SMN2ALDH1A1CA2POLBTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2949332-A2 | COMPOSITIONS FOR THE SYSTEMIC TREATMENT OF PATHOLOGICAL CONDITIONS RESULTING FROM OXIDATIVE STRESS AND/OR REDOX IMBALANCE | Nuevas Alternativas Naturales Thermafat, S.A.P.I. de C.V. (MX) | 2015-12-02 | — | — | EP | disclosed |
| US-8513484-B2 | Fish cancer model | TEMASEK LIFE SCIENCES LABORATORY LIMITED (SG) | 2013-08-20 | — | — | US | disclosed |
| US-20130136725-A1 | COMPOSITIONS FOR SYSTEMIC TREATMENT OF PATHOLOGICAL CONDITIONS RESULTING FROM OXIDATIVE STRESS AND/OR REDOX IMBALANCE | NUEVAS ALTERNATIVAS NATURALES THERMAFAT, S.A.P.I. DE C.V. (MX) | 2013-05-30 | — | — | US | disclosed |
| US-8389005-B2 | Systemic treatment of pathological conditions resulting from oxidative stress and/or redox imbalance | NUEVAS ALTERNATIVAS NATURALES THERMAFAT, S.A.P.I. DE C.V. (MX) | 2013-03-05 | — | — | US | disclosed |
| US-8361514-B2 | Systemic treatment of pathological conditions resulting from oxidative stress and/or redox imbalance | Nuevas Alternatives Naturales Thermafat, S.A.P.I. de C.V. (MX) | 2013-01-29 | — | — | US | disclosed |
| US-20120270259-A1 | FISH CANCER MODEL | TEMASEK LIFE SCIENCES LABORATORY LIMITED (SG) | 2012-10-25 | — | — | US | disclosed |
| US-8242326-B2 | Fish cancer model | TEMASEK LIFE SCIENCES LABORATORY LIMITED (SG) | 2012-08-14 | — | — | US | disclosed |
| US-20090304819-A1 | Systemic Treatment of Pathological Conditions Resulting from Oxidative Stress and/or Redox Imbalance | SULFAGENIX, INC. | 2009-12-10 | — | — | US | disclosed |
| US-20090181081-A1 | Systemic Treatment of Pathological Conditions Resulting From Oxidative Stress and/or Redox Imbalance | SULFAGENIX, INC. | 2009-07-16 | — | — | US | disclosed |
| US-20080289054-A1 | Fish Cancer Model | TEMASEK LIFE SCIENCES LABORATORY LIMITED (SG) | 2008-11-20 | — | — | US | disclosed |
| EP-1906727-A1 | FISH CANCER MODEL | Temasek Life Sciences Laboratory Limited (SG) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007011312-A1 | FISH CANCER MODEL | TEMASEK LIFE SCIENCES LABORATORY LIMITED (SG) | 2007-01-25 | — | — | WO | disclosed |
| US-20030235571-A1 | Systemic treatment of pathological conditions resulting from oxidative stress and/or redox imbalance | GOJON-ROMANILLOS GABRIEL (MX) | 2003-12-25 | — | — | US | disclosed |