Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.49 |
| ▸ | FAP | Q12884 | 2/20 | 0.49 |
| ▸ | PREP | P48147 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PPID | Q08752 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3943991 | 0.98 | TSHR (0.50) | DPP4FAPPREPTSHRATM | |
| SCHEMBL17737713 | 0.96 | DPP4 (0.49) | DPP4FAPPREPTSHRATM | |
| SCHEMBL17084546 | 0.85 | CYP1A2 (0.46) | DPP4FAPPREPRAB9ANPSR1 | |
| SCHEMBL8230809 | 0.83 | TDP1 (0.50) | DPP4FAPPREPNPSR1L3MBTL1 | |
| SCHEMBL2386717 | 0.82 | FAP (0.41) | DPP4FAPPREPTSHRPPID | |
| SCHEMBL3316350 | 0.82 | FAP (0.41) | DPP4FAPPREPTSHRNPSR1 | |
| SCHEMBL10662926 | 0.82 | FAP (0.41) | DPP4FAPPREPNPSR1KMT2A | |
| SCHEMBL13135936 | 0.82 | HTT (0.52) | DPP4FAPPREPTSHRRAB9A | |
| SCHEMBL2907861 | 0.80 | ATM (0.48) | DPP4TSHRATMPPIDRAB9A | |
| SCHEMBL8353377 | 0.79 | TSHR (0.53) | DPP4TSHRATMPPIDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | claimed |
| WO-2013033270-A2 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2013-03-07 | — | — | WO | disclosed |