Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | SMARCA2 | P51531 | 5/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 5/20 | 0.43 |
| ▸ | SMARCA4 | P51532 | 4/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3288856 | 0.82 | JAK3 (0.46) | JAK3HTTLMNASMN1; SMN2NCOA3 | |
| SCHEMBL4866883 | 0.80 | JAK1 (0.43) | JAK3SMN1; SMN2SMARCA2PBRM1SMARCA4 | |
| SCHEMBL4865463 | 0.80 | JAK1 (0.43) | JAK3SMN1; SMN2SMARCA2PBRM1SMARCA4 | |
| SCHEMBL6220849 | 0.80 | JAK1 (0.43) | JAK3SMN1; SMN2SMARCA2PBRM1SMARCA4 | |
| SCHEMBL4865454 | 0.80 | JAK1 (0.43) | JAK3SMN1; SMN2SMARCA2PBRM1SMARCA4 | |
| SCHEMBL4865461 | 0.80 | JAK1 (0.43) | JAK3SMN1; SMN2SMARCA2PBRM1SMARCA4 | |
| SCHEMBL4866890 | 0.80 | JAK1 (0.43) | JAK3SMN1; SMN2SMARCA2PBRM1SMARCA4 | |
| SCHEMBL28715492 | 0.79 | GFER (0.48) | JAK3HTTLMNASMN1; SMN2NCOA3 | |
| SCHEMBL3291095 | 0.78 | AR (0.52) | JAK3HTTLMNASMN1; SMN2NCOA3 | |
| SCHEMBL4674143 | 0.75 | JAK3 (0.45) | JAK3HTTLMNASMN1; SMN2NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1413286-B1 | Dyeing composition comprising at least one heterocyclic oxidation base and at least one substituted 2,3-diaminopyridine as a coupling agent | OREAL (FR) | 2009-04-22 | — | — | EP | disclosed |
| EP-1413286-A1 | Dyeing composition comprising at least one heterocyclic oxidation base and at least one substituted 2,3-diaminopyridine as a coupling agent | L'OREAL (FR) | 2004-04-28 | — | — | EP | disclosed |