Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952210 | 0.92 | ALDH1A1 (0.43) | OPRK1PREPALDH1A1TGM2CTSL | |
| SCHEMBL3950959 | 0.81 | ALDH1A1 (0.46) | OPRK1PREPALDH1A1CTSLCTSB | |
| SCHEMBL4052066 | 0.78 | ALDH1A1 (0.47) | OPRK1PREPALDH1A1CTSLCTSB | |
| SCHEMBL2084495 | 0.75 | PREP (0.45) | PREP | |
| SCHEMBL1816147 | 0.72 | PREP (0.49) | OPRK1PREPALDH1A1 | |
| SCHEMBL17293555 | 0.72 | PREP (0.49) | OPRK1PREPALDH1A1 | |
| SCHEMBL2084198 | 0.70 | PREP (0.48) | PREP | |
| SCHEMBL21225368 | 0.70 | CYP2D6 (0.46) | ALDH1A1 | |
| SCHEMBL2084143 | 0.69 | PREP (0.47) | PREPALDH1A1 | |
| SCHEMBL2084228 | 0.69 | ALDH1A1 (0.44) | OPRK1PREPALDH1A1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888618-A4 | ANALOGS OF GLYCYL-PROLYL-GLUTAMATE | NEUREN PHARMACEUTICALS LTD (NZ) | 2009-07-15 | — | — | EP | disclosed |
| EP-1888618-A2 | ANALOGS OF GLYCYL-PROLYL-GLUTAMATE | Neuren Pharmaceuticals Limited (NZ) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006127702-A2 | ANALOGS OF GLYCYL-PROLYL-GLUTAMATE | NEUREN PHARMACEUTICALS LIMITED (NZ) | 2006-11-30 | — | — | WO | disclosed |