Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 18/20 | 0.74 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952171 | 1.00 | HTR6 (0.74) | HTR6PKMHTR2CHTR2B | |
| SCHEMBL13840416 | 0.90 | HTR6 (0.71) | HTR6 | |
| SCHEMBL3904064 | 0.88 | HTR6 (0.58) | HTR6HTR2CHTR2B | |
| SCHEMBL3904061 | 0.88 | HTR6 (0.58) | HTR6HTR2CHTR2B | |
| SCHEMBL1697568 | 0.85 | HTR6 (1.00) | HTR6 | |
| SCHEMBL3912579 | 0.81 | HTR6 (0.62) | HTR6 | |
| SCHEMBL3902324 | 0.81 | HTR6 (0.57) | HTR6 | |
| SCHEMBL3913194 | 0.78 | HTR6 (0.56) | HTR6 | |
| SCHEMBL3913193 | 0.78 | HTR6 (0.56) | HTR6 | |
| SCHEMBL3907933 | 0.73 | HTR6 (0.54) | HTR6HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2076489-A1 | ARYLSULFONAMIDYL TETRALIN DERIVATIVES AND USES THEREOF | F. Hoffmann-Roche AG (CH) | 2009-07-08 | — | — | EP | disclosed |
| WO-2007147762-A1 | ARYLSULFONAMIDYL TETRALIN DERIVATIVES AND USES THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2007-12-27 | — | — | WO | disclosed |